International Journal of Drug Delivery Technology
Volume 15, Issue 1

Orange Peel Extract Silver Nanoparticles: Formulation and Characterization for Potential Anticancer Activity 

Arbaz Khan, Jyotsana Suyal*, Ishika Chakraborty, Pallavi Ghildiyal, Abhishek Singh 

Department of Pharmaceutics, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun Uttrakhand, 248007 

Received: 8th Jun, 2024; Revised: 14th Dec, 2024; Accepted: 5th Jan, 2025; Available Online: 25th Mar, 2025 

ABSTRACT

Objective: The current study was attempted to develop silver nanoparticles from orange peel extract designed for the management of lung cancer.

Method: Silver nanoparticles were prepared using orange peel extract and nanoparticles forming material in an organic solvent to form an effective solution. The nanoparticles were formed by the solvent evaporation method.  Nanoparticles are extremely small units whose size is articulated in nano-meters (nm; 1 nm = 10−9 meters). Both naturally occurring and artificially produced nanoparticles are products of human activity. To transport medications to the target region, nanoparticles (NP) play a crucial function and can conjugate with different pharmaceuticals in a variety of ways. The prepared silver nanoparticle were characterized i.e. UV spectroscopy, FTIR, XRD, SEM, Anticancer activity.

Results: Orange peel silver nanoparticles exhibit satisfactory parameters results which shows this nanoparticle can be used for anticancer activity and both the compounds have good compatibility and effectiveness in the cancer cells and sustainability for the growth of the cancer.

Silver nanoparticles are one of the most prominent compound for cancer activity.The best average sizes of the particles were around 67.94nm from the orange peel extract.

Keywords:Nanoparticle, Orange peel extract, anti-cancer, silver nanoparticle.

How to cite this article Arbaz Khan, Jyotsana Suyal, Ishika Chakraborty, Pallavi Ghildiyal, Abhishek Singh. Orange Peel Extract Silver Nanoparticles: Formulation and Characterization for Potential Anticancer Activity.  International Journal of Drug Delivery Technology. 2025;15(1):168-74. doi: 10.25258/ijddt.15.1.23

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