International Journal of Drug Delivery Technology
Volume 15, Issue 1

Advancements in HPTLC Method for Ciprofloxacin and Tinidazole

Narendra R. Dighade1*, Hina D. Mehta1, Swati Gaikwad1, Vinod M. Thakare1, Brij Singh2 

1Nagpur College of Pharmacy, Wanadongri, Hingna Road Nagpur 441110, India

2Datta Meghe Medical College, Wanadongri, Hingna Road Nagpur 441110, India 

Received: 24th Sep, 2024; Revised: 16th Dec, 2024; Accepted: 6th Jan, 2025; Available Online: 25th Mar, 2025 

ABSTRACT

Now a days multicomponent formulations are becoming more popular in order to ensure timely and complete medication in multidrug therapy and enhancement of patient compliance.

Through, analytical methods for single drug are extensively available, still due to complexity in multicomponent formulation, method development for the individual active component is sort of challenge for the analytical chemist. Information in the books also do not provide methods of simultaneous estimation of the newly developed and marketed formulations. Most of the methods are available after separation of active components, which become tedious, time consuming, and lack of accuracy.Therefore, the attention in the present project was focused on to foster simple easy economical reproducible analytical method for the assessment of Ciprofloxacin (CP) and Tinidazole (TZ) in combinations by using HPTLC Method.

Keywords: HPTLC method development, Simultaneous estimation, Ciprofloxacin (CP), Tinidazole (TZ), Combined dosage form analysis

How to cite this article: Narendra R. Dighade , Hina D. Mehta, Swati Gaikwad, Vinod M. Thakare, Brij Singh. Advancements in HPTLC method for Ciprofloxacin and Tinidazole. International Journal of Drug Delivery Technology. 2025;15(1):50-56. doi: 10.25258/ijddt.15.1.7

REFERENCES

  1. Sherma J, Fried B. Handbook of Thin-Layer Chromatography. CRC Press; 2003.
  2. Sethi PD. HPTLC: Quantitative Analysis of Pharmaceutical Formulations. CBS Publishers & Distributors; 1996.
  3. Nyiredy S. Progress in Thin-Layer Chromatography and Related Techniques, Vol. 7. Wiley-VCH; 2001.
  4. Reich E, Schibli A. High-Performance Thin-Layer Chromatography for the Analysis of Medicinal Plants. Thieme; 2007.
  5. Indian Pharmacopoeia. Ministry of Health and Family Welfare, Govt. of India, The Indian Pharmacopoeia Commission, Ghaziabad; 2010. Vol II, p. 1090.
  6. British Pharmacopoeia. The British Pharmacopoeia Commission, London; 2001. p. 346.
  7. United States Pharmacopoeia. United States Pharmacopoeial Convention Inc.; 2000. p. 418.
  8. Sharma R, Pathodiya G, Mishra GP, Jitendra S. Journal of Pharmacy Research. 2011;4(3):859-861.
  9. Patel SA, Patel NM, Patel MM. Indian J Pharm Sci. 2006;10:665-667.
  10. Jadhav V, Kashew JK, Mishra P. Indian J Pharm Sci. 2005;8:482-484.
  11. Michalska K, Pajchel G, Tyski SJ. Chromatogr A. 2004;1051(1-2):267-272.
  12. Feng YL, Dong CJ. Chromatogr. 2004;42(9):474-477.