International Journal of Drug Delivery Technology
Volume 15, Issue 2

Analyzing Moringa oleifera Extract’s Antidiabetic Effects with an Osmotic Pump Delivery System

Nehere S V*, Bhise K

Allana College of Pharmacy, K. B. Hidayatullah Road, Azam Campus, Pune - 411001, Maharashtra, India

Received: 14th Mar, 2025; Revised: 17th Apr, 2025; Accepted: 12th May, 2025; Available Online: 25th Jun, 2025

ABSTRACT

The growing prevalence of diabetes necessitates novel therapeutic approaches that enhance both efficacy and patient adherence. This study examines the antidiabetic efficacy of Moringa oleifera extract delivered via an osmotic pump system in a streptozotocin-induced diabetic rat model, hypothesizing that this advanced delivery mechanism improves bioavailability and extends the duration of pharmacological action. The formulation comprised Moringa oleifera extract, quercetin, and several excipients. Experimental evaluations measured fasting blood glucose levels, bodyweight changes, and biochemical markers of hepatic and renal function, comparing the osmotic pump–based treatment group to standard diabetic controls. Statistical analyses will discern the significance of observed therapeutic benefits, thereby contributing to the evidence base for phytopharmaceuticals in diabetes management and underscoring the potential of osmotic drug delivery systems to enhance clinical outcomes.

Keywords: Moringa oleifera extract, Osmotic pump, Antidiabetic activity, Quercetin, Drug delivery system

How to cite this article: Nehere S V, Bhise K . Analyzing Moringa oleifera Extract’s Antidiabetic Effects with an Osmotic Pump Delivery System. International Journal of Drug Delivery Technology. 2025;15(2):452-60 doi: 10.25258/ijddt.15.2.11

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