International Journal of Drug Delivery Technology
Volume 15, Issue 3

Nephroprotective, Hepatoprotective and Toxicological Studies of Vigna mungo Aqueous Extract

Shivanee G Phalphale*, Kratika Daniel

Faculty of Pharmacy, Oriental University, Indore, MP-453555, India

Received: 3rd Jul, 2025; Revised: 14th Aug, 2025; Accepted: 8th Sep, 2025; Available Online: 25th Sep, 2025

ABSTRACT

Hepatitis and nephropathy are significant global public health issues. The liver plays a crucial role in the body's glucose, protein, and lipid metabolism while also facilitating the elimination of waste products and harmful metabolites, thereby preventing toxicity. Similarly, the kidneys, being key components of the excretory system, are particularly vulnerable to a wide array of toxic agents, chemicals, and drug-related injuries. About 80% of people worldwide use traditional medicine to treat a variety of illnesses, according to the World Health Organisation (WHO). However, scientific studies reveal that only about 1% of these plants exhibit therapeutic potential when consumed in extract form by humans. Given the absence of stable liver and kidney protective drugs in conventional allopathic medicine, herbal remedies play a vital role in managing liver and kidney disorders. Herbal medicines are often considered safe and free from significant side effects due to their natural origin and widespread availability. The seeds of Vigna mungo are traditionally utilised in treatments for conditions such as paralysis, rheumatism, nervous system disorders, fever, and as a diuretic and tonic. These seeds are rich in bioactive compounds, including phenolic compounds, tannins, saponins, flavonoids, carbohydrates, proteins, amino acids, lipids, ascorbic acid, and enzymes. However, the hepatoprotective effects have not been extensively studied using additional experimental models. Moreover, there is a lack of systematic and scientific analysis regarding their potential renal effects in the existing literature.

Keywords: Nephroprotective, Hepatoprotective, Toxicological, Kidney, Liver, etc.

How to cite this article: Shivanee G Phalphale, Kratika Daniel. Nephroprotective, Hepatoprotective and Toxicological Studies of Vigna mungo Aqueous Extract. International Journal of Drug Delivery Technology. 2025;15(3):1034-39. doi: 10.25258/ijddt.15.3.19

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