International Journal of Drug Delivery Technology
Volume 15, Issue 3

Optimizing Patient Care: A Review of Polypharmacy and the Vital Role of Pharmacists in Prevention

Grandhi Surendra1, Sushma N2, Venkata Kishore Darisi3, Ch K V L S N Anjana Male1* 

1School of pharmacy, ITM University, Gwalior, Madhya Pradesh, India

2 KL college of Pharmacy, KL University, Vaddeswaram, Guntur, Andhra Pradesh-522302, India

3Shadan college of Pharmacy, Peeran cheru, Hyderabad, Telangana, India 

Received: 10th Sep, 2024; Revised: 17th Jun, 2025; Accepted: 2nd Jul, 2025; Available Online: 25th Sep, 2025 

ABSTRACT

Polypharmacy is a prominent issue within the pharmacy field, denoting the simultaneous utilization of numerous drugs by an individual patient. The aforementioned phenomenon has experienced a notable rise within contemporary healthcare settings, primarily attributed to the advancing age of the population and the escalating prevalence of chronic illnesses. Although the utilization of multiple medications, known as polypharmacy, may be essential for the management of intricate health conditions, it presents significant challenges. This review aims to examine the fundamental elements of polypharmacy, encompassing its etiology and ramifications. The analysis will explore the underlying variables contributing to this occurrence. Furthermore, this paper will examine the detrimental consequences associated with polypharmacy, encompassing heightened probabilities of medication errors, drug interactions, and adverse drug responses. The significance of medication evaluation and management in tackling polypharmacy will also be emphasized in the review. Pharmacists occupy a pivotal position in the process of optimizing pharmaceutical regimens, safeguarding patient well-being, and augmenting therapeutic results. Moreover, it will underscore the necessity of interprofessional coordination among healthcare practitioners to address and alleviate the potential hazards linked to polypharmacy. Polypharmacy presents a multifaceted issue within modern healthcare, carrying significant consequences for both patient safety and overall welfare. Pharmacists play a crucial role in resolving this matter and advocating for the logical, safe, and effective utilization of medications, leveraging their specialized knowledge in drug management.

Keywords: Polypharmacy, Healthcare, Chronic illness, Utilization, Ramification, Patient safety.

How to cite this article: Grandhi Surendra, Sushma N, Venkata Kishore Darisi, Ch K V L S N Anjana Male. Optimizing Patient Care: A Review of Polypharmacy and the Vital Role of Pharmacists in Prevention. International Journal of Drug Delivery Technology. 2025;15(3):1372-77. doi: 10.25258/ijddt.15.3.59

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