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Y. Srinivasa Rao
K. Sree Deepthi
K.P. R. Chowdary


Microemulsions are clear, transparent, thermodynamically stable dispersions of oil and water, stabilized by an interfacial film
of surfactant frequently in combination with a co-surfactant. Recently, there has been a considerable interest for the
microemulsion formulation, for the delivery of hydrophilic as well as lipophilic drug as drug carriers because of its improved
drug solubilization capacity, long shelf life, easy of preparation and improvement of bioavailability. In this present review, we
discuss about the various advantages of microemulsion in pharmaceuticals, along with its preparation, evaluation and research
work carried out on microemulsions.

Article Details

Author Biography

Y. Srinivasa Rao, Vignan Institute of Pharmaceutical Technology Duvvada, Visakhapatnam-46, Andhra Pradesh, India. Ph.No:0891-2511222


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Table 1: Research Work carried out on Microemulsions
Drug Name Route Purpose/Result
Flurbiprofen7] Parenteral Increased the solubility
Apormorphine HCL8] Transdermal Increased the permeability
Ketoprofen9] Transdermal Enhancement of permeability
Prilocainne-HCL10] Transdermal Increased the solubility
Estradiol11] Transdermal Improvement in solubilization
Aceclofenac12] Dermatological Increased the solubility
Piroxicam13] Oral Increased the solubility
Diclofenac14] Transdermal Permeability enhancement
Dexamethasone15] Topical Ocular Enhanced the Bioavailability
Chloramphenicol16] Ocular Increased the solubility
Ibuprofen17] Parenteral Increased the solubility
Sumatriptan18] Intranasal Enhanced the Bioavailability
Ibuprofen19] Topical Increasing the solubility
Doxorubicin20] - Increasing the Stability
Itraconazole21] Parenteral For better absorption
Timolol22] Ophthalmic For better absorption
Terbinafine23] Transdermal Permeability enhancement
Fenofibrate24] Self-Micro emulsifying Increasing the solubility
Progesterone25] Dermal Increased the chemical Stability
IJDDT, October-December 2009, Vol.1, Issue 2(39-41) 40
Y. Srinivasa Rao et al. / Microemulsions: A novel drug carrier system
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