Synthesis, Characterization and Antibacterial Activity of Some Transition Metal Complexes Derived From The Ligand N-Benzylimidazole Against Methicillin-Resistantt Staphylococcus Aureus (Mrsa)

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Zainab Nashaat Al-Saadi
Abbas Washeel Salmani
Hayder Dawood Arkawazi
Michaele J Hardie

Abstract

Metal complexes of the ligand N-benzylimidazole (BnIm) and their in vitro antibacterial study are reported. The complexes of Co(II), Ni(II), Cu(II), Zn(II), and Ag(I) were synthesized by the reaction of the ligand with appropriate metal salt in 1:4 metal to ligand mole ratio. All the synthesized ligand and their complexes were characterized by physicochemical and spectroscopic techniques. Further, the compounds were screened for their antibacterial activity against a multi-resistance strain of Staphylococcus aureus (MRSA) using ciprofloxacin as a standard antibiotic. In general, all the tested compounds showed antibacterial activities at minimum inhibition concentration (MIC) level.


How to cite this article: Al-Saadi, Z.N., Salman, A.W., Arkawazi, H.D. and Hardie, M.J. (2019). Synthesis, Characterization and Antibacterial Activity of Some Transition Metal Complexes Derived From The Ligand N-Benzylimidazole Against Methicillin-Resistantt Staphylococcus Aureus (Mrsa). International Journal of Drug Delivery Technology, 9(4): 666-670.


Source of support: Nil.
Conflict of interest: None.

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Research Article