Synthesis of Molecularly Imprinted Polymers for estimation of Aspirin by Using Different Functional Monomers

Fatma N Abd, Yehya Kamal Al-Bayati, Baker A Joda


We have created a new technique with high sensitivity, low price, and high stability. This technique is based on a molecularly impressed polymer (MIP) using a functional monomer called methyl methacrylic acid (MAA) and styrene. Appropriate cross-linker and aspirin (AS) template to produce monolithic solid-phase micro-extraction (SPME) fiber. Also, a polymer was created without selective binding locations, which was called a non-imprinted polymer (NIP). (SPME) all these analytical techniques used for the extraction, preconcentration, and selective determination of aspirin (AS) and its derivatives with Uv-vis double beam spectrophotometer. The firmness, stability, and durability of the manufactured fiber offer it its essential position in SPME. Specimens were obtained from Aspirin devices Analytic testing was conducted using UV-vis and Electron Microscopy Scanning (SEM) and FTIR. The relative normal deviations (RSD percent) for four drug-repeated studies for three readings are a range of (at 30-60 ppm AS) percent (1.20-3.61). The comparative recoveries (93.63-99.71) acquired for AS are within the range.


Aspirin, Molecularly imprinted polymer, Solid-phase extraction.

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