Synthesis, Characterization and Antibacterial Activity of Some Transition Metal Complexes Derived From The Ligand N-Benzylimidazole Against Methicillin-Resistantt Staphylococcus Aureus (Mrsa)

Zainab Nashaat Al-Saadi, Abbas Washeel Salman, Hayder Dawood Arkawazi, Michaele J Hardie

Abstract


Metal complexes of the ligand N-benzylimidazole (BnIm) and their in vitro antibacterial study are reported. The complexes of Co(II), Ni(II), Cu(II), Zn(II), and Ag(I) were synthesized by the reaction of the ligand with appropriate metal salt in 1:4 metal to ligand mole ratio. All the synthesized ligand and their complexes were characterized by physicochemical and spectroscopic techniques. Further, the compounds were screened for their antibacterial activity against a multi-resistance strain of Staphylococcus aureus (MRSA) using ciprofloxacin as a standard antibiotic. In general, all the tested compounds showed antibacterial activities at minimum inhibition concentration (MIC) level.

Keywords


Antibacterial, Imidazole; Metal complexes, Methicillin-resistantt Staphylococcus aureus (MRSA), MIC value.

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DOI: https://doi.org/10.25258/ijddt.v9i4.25

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