Comparative Assessment of the Antioxidant Potential of Different Parts of Delonix regia
Singh S1, Sardana S1*, Verma I2
1Amity Institute of Pharmacy, Amity University, Gurugram, Haryana, India
2MM College of Pharmacy, Maharishi Markandeshwar Deemed-to-be-University, Ambala, Haryana, India
Received: 20th December, 2023; Revised: 16th January, 2024; Accepted: 10th February, 2024; Available Online: 25th March, 2024
ABSTRACT
The flamboyant tree, or Delonix regia, has attracted a lot of interest due to the widespread belief that it can be used as a powerful antioxidant. The search for natural antioxidants has taken on paramount relevance as the world faces increasing health problems attributed to oxidative stress. D. regia, a native of Madagascar, can be found all across the tropics and subtropics and is highly regarded for its medicinal value and beautiful red flowers. The complex phytochemical composition of D. regia includes a number of bioactive compounds that might prevent oxidative damage to biomolecules. Flavonoids, tannins, phenolic acids, carotenes, and tocopherols are all examples of these substances. The antioxidant action of different parts of D. regia is comprehensively examined and clarified in this work, from its broad scope in direct radical scavenging to its fine-tuning of endogenous antioxidant enzymes. The antioxidant capabilities of D. regia have been studied for their potential to address a broad spectrum of illnesses and health conditions, such as cancer, diabetes, cardiovascular disease, neurological disorders, and a number of skin issues. The importance of utilizing nature’s bounty in the hunt for novel remedies to oxidative stress-related illnesses is underscored by this study’s addition to the growing body of knowledge concerning the antioxidant effects of D. regia. Further research is recommended to explore the pharmacological properties of D. regia to fully harness its medicinal potential for the advancement of human health and well-being.
Keywords: Delonix regia, Antioxidants.
International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.1.29
How to cite this article: Singh S, Sardana S, Verma I. Comparative Assessment of the Antioxidant Potential of Different Parts
of Delonix regia. International Journal of Drug Delivery Technology. 2024;14(1):198-202.
REFERENCES
- Modi A, Mishra V, Bhatt A, Jain A, Mansoori MH, Gurnany E, Kumar V. Delonix regia: historic perspectives and modern phytochemical and pharmacological Chinese Journal Natural Medicine, 2016 Jan,14(1):31-39.
- Shabir G, Anwar F, Sultana B, Khalid ZM, Afzal M, Khan QM, Ashrafuzzaman M. Antioxidant and Antimicrobial Attributes and Phenolics of Different Solvent Extracts from Leaves, Flowers and Bark of Gold Mohar [Delonix regia (Bojer ex ) Raf.]. Molecules. 2011, 16(9):7302-7319
- Rahman M, Hasan N, Das AK, Hossain T, Jahan R, Khatun A, Rahmatullah M. Effect of Delonix regia leaf extract on glucose tolerance in glucose-induced hyperglycemic mice. African Journal of Traditional, Complementary and Alternative Medicines. 2011, 8(1):34-36.
- Singh and Kumar SN. A review: introduction to genus Delonix. World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS), 2014, 3(6): 2042-55.
- Salem M. Evaluation of the antibacterial activities of stem bark extracts of Delonix regia and Erythrina humeana grown in Egypt. Journal of Forest Products and Industries, 2013, 2: 48-52.
- Aqil F, Ahmad I, Mehmood Z. Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal Turkish Journal of Biology, 2006, 30: 177-183.
- Jungalwala F, Cama Carotenoids in Delonix regia (Gul Mohr)flower. Biochemical Journal, 1962, Oct 85(1): 1-8
- Azab S, Daim A and Omayma E. Phytochemical, cytotoxic, hepatoprotective and antioxidant properties of Delonix regia leaves extract. Medicinal Chemistry Research, 2013, 22: 4269-4277.
- Vivek MN, Sachidananda HC, Manasa M, Kambar Antimicrobial and antioxidant activity of leaf and flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum. Journal of Applied Pharmaceutical Science, 2013, 3: 64-71.
- Chai WM, Shi Y, Feng HL, Qiu L, Zhou HC, Deng ZW, Yan CL, Chen NMR, HPLC-ESI-MS, and MALDI-TOF MSanalysis of condensed tannins from Delonix regia (Bojer ex Hook.) Raf. and their bioactivities. Journal of Agricultural and Food Chemistry. 2012 May 16;60(19):5013-5022.
- Rani PMJ, Kannan PSM, Kumaravel Screening of antioxidant activity, total phenolics and gas chromatograph and mass spectrometer (GC-MS) study of Delonix regia. African Journal of Biochemistry Research, 2011, 5: 341-347.
- Rahman FB, Ahmed S, Noor P, Rahman MMM, Huq SMA, Akib MTE, Shohael AM. A comprehensive multi-directional exploration of phytochemicals and bioactivities of flower extracts from Delonix regia (Bojer ex Hook.) Raf., Cassia fistula L. and Lagerstroemia speciosa Biochemistry and Biophysics Report, 2020, Sep 11:24.
- Bhatt GD, Bindhupriya M, Salam J. Establishment of Herbal Garden in the Galgotias University Campus - An Ex-situ Conservation Approach. International Journal of Plant and Environment. 2023, 9(2): 143-149.
- Yen C. and Hsieh PP. Antioxidative activity and scavenging effects on active oxygen of xylose‐lysine Maillard reactionproducts. Journal of the Science of Food and Agriculture, 1995,67(3): 415-420.
- Ruch RJ, Cheng SJ, Klaunig Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis. 1989 Jun;10(6):1003-1008.
- Shukla S, Mehta A, Bajpai VK, Shukla S. In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of Stevia rebaudiana Bert. Food and Chemical Toxicology 2009 Sep;47(9):2338-43.
- Marcocci L, Maguire JJ, Droy-Lefaix MT, Packer The nitric oxide-scavenging properties of Ginkgo biloba extract EGb 761. Biochemical and biophysical research communications. 1994 Jun 15;201(2):748-755.
- Blois, M.S. Antioxidant determinations by the use of a stable free radical. Nature, 1958. 181(4617): 1199-1200.
- Ahmed MS, Khan IJ, Aman S, Chauhan S, Kaur N, Shriwastav S, Goel K, Saini M, Dhankar S, Singh TG, Dev J, & Mujwar S. Phytochemical investigations, in-vitro antioxidant, antimicrobial potential, and in-silico computational docking analysis of Euphorbia milii Des Journal of Experimental Biology and Agricultural Sciences, 2023, 11(2): 380–393.