International Journal of Drug Delivery Technology
Volume 14, Issue 1

Preliminary Phytochemical Investigation, GC-MS Characterization, In-vitro Antioxidant Potential of Ethanolic Leaf Extract of Melastomataceae Species Memecylon malabaricum (C.B. Clarke) Cogn.

RR Manjula, Thirumal M*

Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.

Received: 25th November, 2023; Revised: 12th December, 2023; Accepted: 20th January, 2024; Available Online: 25th March, 2024

ABSTRACT

The leaf extracts of Memecylon malabaricum were subjected to a detailed phytochemical investigation as part of this study. Based on the findings of this investigation, it was discovered that the leaf extracts included a wide range of bioactive components. These components included carbohydrates, glycosides, flavonoids, tannins, terpenes, phenols, and saponins. Throughout the whole of the experiment, the only extract that displayed phytosterols was the ethanolic extract. The findings of the DPPH, ABTS, total antioxidant assay-FRAP, superoxide anion radical scavenging assay, and total antioxidant assay-CUPAC assays demonstrated that all of the samples, but sample A in particular, had antioxidant qualities that were encouraging. This was the conclusion that was reached. A GC-MS analysis was used to thoroughly examine the chemical configuration of the leaves of M. malabaricum. According to the findings of this inquiry, 60 distinct components were examined. The legitimacy of the therapeutic potential of M. malabaricum is gained as a result of these results, which also pave the way for more study into the plant’s possible applications in the fields of pharmacology and medicine.

Keywords: Melastomataceae, Memecylon malabaricum (C.B.Clarke) Cogn, GC-MS analysis of ethanolic leaf extract, Antioxidant activity, Total antioxidant DPPH, ABTS radical scavenging activity, FRAP, Superoxide anion radical scavenging activity.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.1.36

How to cite this article: Manjula RR, Thirumal M. Preliminary Phytochemical Investigation, GC-MS Characterization, In-vitro Antioxidant Potential of Ethanolic Leaf Extract of Melastomataceae Species Memecylon malabaricum (C.B. Clarke) Cogn. International Journal of Drug Delivery Technology. 2024;14(1):246-256.

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