International Journal of Drug Delivery Technology
Volume 14, Issue 2

Validated Area Under Curve Quantitative UV Spectrophotometric Analysis of Rebamipide in Drug Formulations

Karajgi SR1*, Kulkarni RV2, Potadar SS1, Ingale Anand2

1Department of Pharmaceutical Quality Assurance, BLDEA’s SSM College of Pharmacy and Research Centre, Vijayapur, Karnataka, India.

2BLDE (Deemed to be University) Bangaramma Sajjan Campus, Vijayapur, Karnataka, India. 

Received: 07th November, 2023; Revised: 19th March, 2024; Accepted: 23rd April, 2024; Available Online: 25th June, 2024 

ABSTRACT

A very simple, accurately perfect, precisely repeatable procedure has been proposed for the estimate of rebamipide in medicines. Evaluation of previous works indicates the fact that, so far no UV spectrophotometric scheme for quantifiable estimate by area under curve technique for the drug rebamipide is not described. Therefore, there was a need to plan a different methodology to analyze the medicine employing dimethyl formamide in the form of solvent. This medication monitors Beer’s law in the range of concentration 20 to 200 µg/mL in the ultraviolet range, particularly areas between 320 and 340 nm for are under curve because the absorption maximum was found to be 330 nm in the selected solvent. The recovery readings proved the offered technique’s accuracy and outcomes were authenticated par accordance with the International Council for Harmonisation (ICH) references. The discoveries were reasoned to be consistent as well as agreeable. As a consequence, this optional technique was successfully used to estimate rebamipide quantitatively in conventional analytical applications.

Keywords: Rebamipide, Area under curve, Estimation, Analysis, UV spectrophotometric. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.2.02

How to cite this article: Karajgi SR, Kulkarni RV, Potadar SS, Anand I. Validated Area Under Curve Quantitative UV Spectrophotometric Analysis of Rebamipide in Drug Formulations. International Journal of Drug Delivery Technology. 2024;14(2):625-629.

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