International Journal of Drug Delivery Technology
Volume 14, Issue 2

Chemical Composition and Antioxidants of Senecio vulgaris (Asteraceae)

Karzan Omer Qader

Department of Biology, College of science, University of Sulaimani, Iraq. 

Received: 02nd December, 2023; Revised: 15th February, 2024; Accepted: 30th May, 2024, Available Online: 25th June,2024 

ABSTRACT

The study included the antioxidant and chemical compounds of methanolic extract of Senecio vulgaris in Iraq. S. vulgaris has a rich history in traditional medicine for treating different health problems. The results gas chromatography-mass spectrometry (GC-MS) chromatogram of S. vulgaris extract showed 19 peaks, which indicates the presence of 19 compounds (phytochemical constituents). Most of the chemical components extracted from S. vulgaris include oleic acid (40.46%), n-Hexadecanoic acid (23.40%), 5,9-dimethyl-2-(1-methylethyl)-1-cyclodecanone (6.52%), octadecanoic acid (3.57%) and 1,2-benzenedicarboxylic acid, bis(2-methylpropyl) ester (3.27%).

The antioxidant activity of overall methanol extract contents of S. vulgaris was determined by adding different concentrations of methanol extract to 2,2-diphenyl-1-picrylhydrazyle (DPPH). The inhibitory activity was evaluated by using five different concentrations of methanol extract of S. vulgaris. The results showed that the antioxidant activity in concentration 3 μL/mL was 41.23%, while the highest antioxidant activity was 98.33% in 25 μL/mL compared with vitamin C, which was 16% in 3 μL/mL and recorded 91.97% in 25 μL/mL. The total antioxidant capacity of S. vulgaris methanol extract was evaluated as vitamin C equivalents per gram. The DPPH radical scavenging potency with a minimum IC50 value in S. vulgaris was

5.64 μL/mL, while vitamin C was 3.09.

Keywords: Antioxidant, GC-MS analysis, Senecio vulgaris, Soxhlet.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.2.70

How to cite this article: Qader KO. Chemical Composition and Antioxidants of Senecio vulgaris (Asteraceae). International Journal of Drug Delivery Technology. 2024;14(2):1066-1070.

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