International Journal of Drug Delivery Technology
Volume 14, Issue 2

Current Updates on the Therapeutic Potential of Diosgenin

Sowmya C*, Thirumal V, Preetika S, Epsiba A

Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, India.

Received: 24th December, 2023; Revised: 16th February, 2024; Accepted: 14th May, 2024; Available Online: 25th June, 2024 

ABSTRACT

Diosgenin (DG) is a naturally occurring steroid saponin that can be obtained from several plants. A lot of the artificial steroidal drugs that are used extensively in the pharmaceutical industry come from diosgenin for the treatment of various disease conditions. DG has various intriguing pharmacological effects, including anticancer, antidepressant, and anti-inflammatory and anti-infectious capabilities. Apart from its health advantages, DG is challenging to utilize in therapeutic applications due to its poor water solubility, bioavailability, and rapid physiological change. The DG nanotechnology for medicine formulations has been tested as a possible therapy for a variety of disorders employing a broad range of ex-vivo, in-vitro, and in-vivo models and delivery methods. Based on this analysis, it is possible to infer that DG is a viable therapeutic alternative for the management of numerous ailments, such as diabetes, cancer, neurological conditions, inflammatory diseases, and skin conditions.

Keywords: Diosgenin, Steroid saponin, Anticancer, Anti-inflammatory, Therapeutic potential of diosgenin.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.2.78

How to cite this article: Sowmya C, Thirumal V, Preetika S, Epsiba A. Current Updates on the Therapeutic Potential of Diosgenin. International Journal of Drug Delivery Technology. 2024;14(2):1124-1129.

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