International Journal of Drug Delivery Technology
Volume 14, Issue 2

Nanotechnology in Ankylosing Spondylitis: Advancements in Drug Delivery and Targeted Therapy

Anuj Kumar1*, Jitendra Singh Chaudhary1, Anubhav Dubey2, Shubham Sanjay Pachorkar3

1Smt. Vidyawati College of Pharmacy, Jhansi, Uttar Pradesh, India.

2Department of Pharmacology, Maharana Pratap College of Pharmacy, Kanpur, Uttar Pradesh, India.

3MET’s Institute of D. Pharmacy, Nashik, Maharashtra, India. 

Received: 17th May, 2024; Revised: 25th May, 2024; Accepted: 02nd June, 2024; Available Online: 25th June, 2024 

ABSTRACT

Ankylosing spondylitis is a chronic inflammatory disorder primarily affecting the spine and the sacroiliac joints, although it is now considered for new drug target possibilities. It is an area in which nanotechnology has shown significant potential. This report offers an extensive review of the formulation design, clinical utility, and current development in the use of nanotechnology for treating AS. The rational design principles of nanotherapeutics, created to modify the myriad processes implicated in AS pathophysiology, were examined. It comprises drug delivery systems, targeting approaches, and release processes. Clinical and preclinical evidence of nanomedicines’ tolerability and effectiveness in AS therapy is reported. In conclusion, this document reflects the recent state of these nanotechnology-based treatments for AS and discusses the author’s future goals in developing novel, powerful treatment strategies that generate strong patient outcomes.

Keywords: Nanotechnology, Ankylosing spondylitis, Drug delivery, Targeted therapy, Nanomedicine, Formulation design, Clinical applications.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.2.82

How to cite this article: Kumar A, Chaudhary JS, Dubey A, Pachorkar SS. Nanotechnology in Ankylosing Spondylitis: Advancements in Drug Delivery and Targeted Therapy. International Journal of Drug Delivery Technology. 2024;14(2):1162-1173.

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