International Journal of Drug Delivery Technology
Volume 14, Issue 2

A Panoramic Review on Gastro-Retentive Floating Drug Delivery System

Latika Bisht1, Tarun Parashar2*, Mansi Butola1, Vikash Jakhmola1

1Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, India.

2School of Pharmacy & Research, Dev Bhoomi Uttarakhand University, Dehradun, Uttarakhand, India. 

Received: 19th January, 2024; Revised: 14th March, 2024; Accepted: 09th May, 2024; Available Online: 25th June, 2024 

ABSTRACT

Floating drug delivery has been demonstrated to be the most efficacious of the numerous gastroretentive drug delivery mechanism strategies. The concept behind this system has drawn substantial interest in recent decades. Several strategies are currently implemented to prolong the stomach residence durations, such as floating drug delivery systems, swelling and expansion systems, polymer bioadhesive systems, deformation systems, high-density, etc., systems, and various delayed emptying gastric devices. From a formulation and technology standpoint, floating drug delivery equipment is a rather simplistic and straightforward approach. Floating delivery of drug systems is one of the GRDFs used to increase stomach residence duration. The floating medication delivery device can persist in the gastrointestinal region for several hours due to its floating action on the stomach contents, extensively enhancing the gastrointestinal residence period of drugs. The main thrust of this review is on the design, factors, characterization, applications, evaluation criteria, and prospective future gastro-retentive floating medication delivery techniques.

Keywords: Floating drug delivery technique, Gastric content, Strategies, Applications, Evaluation. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.2.91

How to cite this article: Bisht L, Parashar T, Butola M, Jakhmola V. A Panoramic Review on Gastro-Retentive Floating Drug Delivery System. International Journal of Drug Delivery Technology. 2024;14(2):1239-1247.

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