International Journal of Drug Delivery Technology
Volume 14, Issue 3

Formulation Development and Evaluation of Transdermal Patches of Apigenin

Fatima Tirkey, Abhishek Dwivedi*

Faculty of Pharmaceutical Sciences, RKDF University, Bhopal, Madhya Pradesh, India 

Received: 25th March, 2024; Revised: 08th July, 2024; Accepted: 04th August, 2024; Available Online: 25th September, 2024

ABSTRACT

Apigenin is a flavonoid that is abundantly present in fruits and vegetables. It has a diverse range of therapeutic properties, including cardioprotective, neuroprotective, analgesic, and cancer-preventive effects. Its safety profile, even at higher doses, makes the compound particularly valuable. Apigenin, along with excipients, was used to formulate patches using the solvent- casting method on a glass mold. Seven distinct batches of patches were formulated using different combinations of polymers. The drug-polymer ratios employed in these formulations were (1:2), (1:3), (1:4), (1:4), (1:(2:8), (1:(1:9), and (1:(2:8) for both drugs. The formulated patches were evaluated and results indicate that the transdermal patches (TP5) have promising results.

Keywords: Apigenin, Transdermal patches, Formulation, Evaluation, Solvent casting. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.14

How to cite this article: Tirkey F, Dwivedi A. Formulation Development and Evaluation of Transdermal Patches of Apigenin. International Journal of Drug Delivery Technology. 2024;14(3):1353-1356.

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