Formulation Development, Evaluation and Anticandidal Screening of Herbal Cream of Trianthema portulacastrum Linn.

Sumeet Dwivedi^1*, Mahavir Chhajed², Sandeep Ashokrao Wathore³, Sonam Upadhya³

¹Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, India.

²Vikrant Institute of Pharmacy and Science, Indore, Madhya Pradesh, India.

³SVP College of Pharmacy, Hatta, Hingoli, Maharashtra, India.

⁴Jai Narain College of Pharmacy, JNCT Professional University, Bhopal, Madhya Pradesh, India. 

Received: 25^th March, 2024; Revised: 08^th July, 2024; Accepted: 06^th August, 2024; Available Online: 25^th September, 2024

ABSTRACT

Trianthema portulacastrum, commonly known as black pigweed (E) and patharchata (H) belongs to the family Lamiaceae is a flowering medicinal pants. The plant contains various bioactive compounds such as trianthenol, leptormol, cinnamic acid, beta cyanin and ecdysterone. Traditionally, almost every part of the plant is used for the treatment of inflammation, fungal infection, pain, liver disorders, etc. In the present study, hydroalcoholic extract of leaves of Trianthema portulacastrum was taken to formulate herbal cream in three different batches, i.e., C-I, C-II and C-III, using different concentrations of the extract and prepared cream. Also, the anti-candidal activity of the herbal cream was determined in the fungus Candida albicans. The results obtained indicated that the herbal cream containing hydroalcoholic extract of the selected plant possesses significant anti-candidal activity and hence it may used in the treatment of fungal infection.

Keywords: Leaves, Extract, Fungus, Formulation, Herbal.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.15

How to cite this article: Dwivedi S, Chhajed M, Wathore SA, Upadhya S. Formulation Development, Evaluation and Anticandidal Screening of Herbal Cream of Trianthema portulacastrum Linn.. International Journal of Drug Delivery Technology. 2024;14(3):1357-1360.

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