International Journal of Drug Delivery Technology
Volume 14, Issue 3

Synthesis, Formulation and Evaluation of Zinc Oxide Nanoparticle of Capparis zeylanica L. Stem

Bhavana Jain1*, Kishore Burade2

1Department of Pharmaceutical Chemistry, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra, India.

2Department of Pharmacognosy and I/C Principal of Government College of Pharmacy, Karad, Maharashtra, India. 

Received: 25th March, 2024; Revised: 08th July, 2024; Accepted: 14th August, 2024; Available Online: 25th September, 2024 

ABSTRACT

The current study’s focus is on using Capparis zeylanica L. stem extract to produce nanosized zinc oxide (ZnO) biologically in a way that is economical, effective, and environmentally safe. The synthesized nanoparticles were characterized using several techniques such as UV-Vis spectroscopy, TEM, FTIR and UV-vis spectroscopy. UV-vis spectroscopy ranges 200 to 400 nm. Having particle size 248 nm having zeta potential -3.5 mV with different groups. The current work examined by formation of gel, which shows good spreadability.

Keywords: Nanoparticles, Zinc oxide, Capparis zeylanica, Particle size, Zeta potential. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.63

How to cite this article: Jain B, Burade K. Synthesis, Formulation and Evaluation of Zinc Oxide Nanoparticle of Capparis zeylanica L. Stem. International Journal of Drug Delivery Technology. 2024;14(3):1700-1703.

REFERENCES

  1. Kumar KK, Kiran V, Choudhary RK, Devhare LD, Gunjal SD. Design Development and Characterization of Nicardipine Solid
  2. Lipid Nano-Particulars. International Journal of Drug Delivery Technology. 2024;14(1):71-78. DOI: 10.25258/ijddt.14.1.12
  3. Huang C, Peng L, Xu X, Lu Y, Wang X, Lan Z, et Preparation and characteristics of a thermosensitive in situ gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol. Journal of Drug Delivery Science and Technology. 2023;89: 104962. DOI: https://doi.org/10.1016/j. jddst.2023.104962
  4. Sheteiwy MS, Shaghaleh H, Hamoud YA, Holford P, Shao H, Qi W, Hashmi MZ, Wu T. Zinc oxide nanoparticles: potential effects on soil properties, crop production, food processing, and food quality. Environmental Science and Pollution Research. 2021 ;28(28):36942-36966.
  5. Santhoshkumar J, Kumar SV, Rajeshkumar Synthesis of zinc oxide nanoparticles using plant leaf extract against urinary tract infection pathogen. Resource-Efficient Technologies. 2017 Dec 1;3(4):459-465. https://doi.org/10.1016/j.reffit.2017.05.001
  6. Akash MS, Rehman K, Akash MS, Rehman Ultraviolet-visible (UV-VIS) spectroscopy. Essentials of pharmaceutical analysis. 2020:29-56.
  7. Bhattacharjee DLS and zeta potential–what they are and what they are not? Journal of controlled release. 2016 Aug 10; 235:337-https://doi.org/10.1016/j.jconrel.2016.06.017
  8. Rao KG, Ashok CH, Rao KV, Chakra CS, Rajendar V. Green synthesis of tio2 nanoparticles using hibiscus flower In Proceedings of the International Conference on Emerging Technologies in Mechanical Sciences 2014 Dec 8 (pp. 79-82).
  9. Bala N, Saha S, Chakraborty M, Maiti M, Das S, Basu R, NandyGreen synthesis of zinc oxide nanoparticles using Hibiscus subdariffa leaf extract: effect of temperature on synthesis, anti- bacterial activity and anti-diabetic activity. RSC Advances. 2015;5(7):4993-5003.
  10. Nurman S, Yulia R, Irmayanti, Noor E, Candra Sunarti T. The optimization of gel preparations using the active compounds of arabica coffee ground nanoparticles. Scientia Pharmaceutica. 2019;87(4):32. https://doi.org/10.3390/scipharm87040032
  11. Zulkurnain EI, Ramli S, Ali AA, James RJ, Kamarazaman IS, Halim H. The Phytochemical and Pharmacological Effects of Hibiscus rosa-sinensis: A Review. International Journal of Pharmaceutical Investigation. 2023;13(3):422-431 DOI:10.5530/ ijpi.13.3.053
  12. Gnana RPM, Devhare LD, Dharmamoorthy G, Khairnar MV, Prasidha R. Synthesis, Characterisation, Molecular Docking Studies and Biological Evaluation of Novel Benzothiazole Derivatives as EGFR Inhibitors for Anti-breast Cancer Agents. International Journal of Pharmaceutical Quality Assurance. 2023;14(3):475-480. DOI: 10.25258/ijpqa.14.3.03
  13. Priya MGR, Prasanth LML, Devhare LD, Yazdan SK, Gunjal S. Synthesis, DNA Binding, Molecular Docking and Anticancer Studies of Copper (II), Nickel (II), and Zinc (II) Complexes of Primaquine-based Ligand. International Journal of Pharmaceutical Quality Assurance. 2024;15(1):69-75. DOI: 25258/ijpqa.15.1.10