International Journal of Drug Delivery Technology
Volume 14, Issue 3

Titanium Dioxide (TiO2): A Versatile Excipient in Pharmaceuticals

Rahul G Ingle, Samiksha S Khobragade*

Datta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education & Research (DMIHER), Deemed to be University, Sawangi (M), Wardha, India. 

Received: 10th August, 2024; Revised: 20th August, 2024; Accepted: 26th August, 2024; Available Online: 25th September, 2024 

ABSTRACT

Titanium dioxide (TiO2) is a commonly used excipient in pharmaceutical formulations, offering several benefits to pharmaceutical products. As a highly insoluble and thermally stable oxide, TiO2 is utilized as an opacifying agent and suspending agent to improve the appearance, stability, and bioavailability of pharmaceutical products. Its high refractive index and high surface area make it an excellent adsorbent and filler material, while its non-toxic and odorless nature ensures its safe use in pharmaceutical applications.

Here, the authors deliberate the properties and major applications of TiO2 as a versatile excipient in pharmaceuticals. The mesmerizing physic-chemical features of TiO2 depend on the size and shape of particles. At present, TiO2 has added countless considerations as an auspicious photocatalyst due to its extraordinary features such as excellent photocatalytic, electronic, and optical features, high stability, and economical and non-toxic nature.

Moreover, the benefits of using TiO2 as an excipient are discussed, including its ability to improve product appearance, stability, and bioavailability. The review also reports the challenges associated with TiO2, including environmental concerns and biocompatibility issues. However, the benefits of TiO2 far outweigh its drawbacks, making it an extensively accepted excipient in pharmaceuticals. Inclusively, this article aims to provide a comprehensive overview of TiO2 as an excipient in pharmaceuticals, highlighting its unique properties, several applications, and benefits.

Keywords: Excipient, Nano-TiO2, Pharmaceuticals, Stability.

International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.78

How to cite this article: Ingle RG, Khobragade SS. Titanium Dioxide (TiO2): A Versatile Excipient in Pharmaceuticals.

International Journal of Drug Delivery Technology. 2024;14(3):1811-1813.

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