International Journal of Drug Delivery Technology
Volume 14, Issue 3

Pharmacological and toxicity concerns of plant Prunus armeniaca including adoptive nanotechnology for precise delivery of their active constituents

Kunal Chandrakar1, Sandeep Tiwari1, Manisha Chandrakar2*, Khomendra Kumar Sarwa3*, Ritesh Patel1

1Kalinga University Raipur, Atal Nagar Nava Raipur, India.

2University College of Pharmacy Raipur, CSVTU Bhilai, Chhattisgarh, India.

3Department of Pharmacy, Government Girls Polytechnic, Raipur, Chhattisgarh, India. 

Received: 15th March, 2024; Revised: 23rd April, 2024; Accepted: 13th July, 2024; Available Online: 25th September, 2024 

ABSTRACT

Prunus armeniaca is a well-known apricot. Its fruit kernel and seed are mostly reported for medicinal use. Neuroprotective, antidiabetic, and anticancer potentials are highlighted in scientific literature. Apart from medicinal applications, various scientific reports are available to confirm its potential toxic effect, especially in producing allergic symptoms, birth defects, and cyanide- like poisoning. Nowadays nanotechnological concepts are well applied in drug delivery systems to improve drug targetability with precision to avoid unnecessary exposure of drugs to tissues. Delivery of active constituents obtained from this plant is also taken as payload in silver and gold nanoparticles for efficacy assessment. The present literature summarizes the potential health benefits, toxicity, and nanotechnological advancement regarding this valuable medicinal plant. The review concise available scientific information in a single platform covering its traditional use, geographical location, and nutritional values.

Keywords: Prunus armeniaca, Nanotechnology, Allergy, Birth defects, Cyanide-like poisoning, Anticancer, Amygdalin. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.80

How to cite this article: Chandrakar K, Tiwari S, Chandrakar M, Sarwa KK, Patel R. Pharmacological and toxicity concerns of plant Prunus armeniaca including adoptive nanotechnology for precise delivery of their active constituents. International Journal of Drug Delivery Technology. 2024;14(3):1818-1828.

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