International Journal of Drug Delivery Technology
Volume 14, Issue 3

An Overview of the Components, Techniques, and Innovation Used for Fast-Dissolving Films

Achal Dingalwar*, Anil Pethe, Tanmay Kopare, Umesh Telrandhe

Department of Pharmaceutics, Datta Meghe College of Pharmacy, DMIHER, Wardha Maharashtra, India. 

Received: 20th January, 2024; Revised: 27th February, 2024; Accepted: 18th July, 2024; Available Online: 25th September, 2024 

ABSTRACT

Fast-dissolving films (FDFs) stand as a cornerstone in modern pharmaceutical innovation, heralded for their unrivaled convenience, patient adherence, and the swift onset of action. Within the realm of this paper lies a meticulous exploration of FDFs, delving deep into their intricate formulation intricacies, manufacturing methodologies, and diverse therapeutic applications. The formulation journey traverses the meticulous selection of film-forming polymers, plasticizers, taste-masking agents, and active pharmaceutical ingredients (APIs), each element meticulously calibrated to achieve optimal efficacy. Diverse production techniques, spanning solvent casting, hot melt extrusion, and spray drying, are scrutinized with precision, shedding light on their inherent advantages and nuanced limitations. Beyond the realm of formulation and manufacturing, this review embarks on an expansive voyage into the vast therapeutic landscape that FDFs traverse. From the treatment areas of central nervous system disorders to the realms of cardiovascular diseases, allergies, and pain management, the versatility and adaptability of FDFs emerge as a beacon of hope for patients and practitioners alike. Yet, amidst the brilliance of FDFs, inherent challenges linger, from stability concerns to the intricate dance of bioavailability and the ever-watchful eye of regulatory scrutiny. However, within these challenges lies the fertile ground for future research and development endeavors, beckoning forth a new era of innovation and advancement in the realm of rapidly dissolving films. This study stands as an indispensable compass, guiding researchers, pharmaceutical scientists, and practitioners toward the forefront of FDF development and implementation.

Keywords: Fast-dissolving film, Delivery system, Fast-dissolving technologies. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.84

How to cite this article: Dingalwar A, Pethe A, Kopare T, Telrandhe U. An Overview of the Components, Techniques, and Innovation Used for Fast-Dissolving Films. International Journal of Drug Delivery Technology. 2024;14(3):1853-1862.

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