International Journal of Drug Delivery Technology
Volume 14, Issue 3

A Review on Proniosomes as a Novel Drug Delivery System

Prasanthi Pakalapati1, Manthina Mohan Varma2*

1Aditya University, Surampalem, College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India.

2Department of Pharmaceutics, Vishnu College of Pharmacy, Bhimavaram, Andhra Pradesh, India. 

Received: 10th August, 2024; Revised: 20th August, 2024; Accepted: 26th August, 2024; Available Online: 25th September, 2024 

ABSTRACT

Proniosomes are desiccated versions of surfactant-coated, water-soluble carrier particles. Before usage, on agitation in heated aqueous solution, they are rehydrated in a matter of minutes to create niosomal dispersion. In storage and transit, proniosomes maintain their physical stability. The drug contained within the proniosomes’ vesicular structure increases the drug’s potency, improves its absorption into the target tissue, and lowers its toxicity. Niosomes are technically more promising than liposomes as drug carriers since they are more chemically stable and don’t have many of the glitches of liposomes, like high cost and problems with phospholipid purity. Focusing on proniosome preparation, characterization, and application in targeted drug delivery, this study highlights their general approaches.

Keywords: Proniosomes, Niosomes, Vesicular, Characterization, applications. International Journal of Drug Delivery Technology (2024); DOI: 10.25258/ijddt.14.3.93

How to cite this article: Pakalapati P, Varma MM. A Review on Proniosomes as a Novel Drug Delivery System. International Journal of Drug Delivery Technology. 2024;14(3):1931-1935.

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