Background: In the maxillary esthetic zone, soft tissue augmentation is essential for successful aesthetic outcomes surrounding implants. The gold standard(subepithelial connective tissue grafts (SCTG)) entail donor site morbidity. An alternative that is less invasive is provided by xenogeneic collagen matrices (XCM). In order to improve soft tissue, this study compares SCTG with XCM in early implant placement. Objective: “This study aims to compare and evaluate the clinical results of soft tissue augmentation using a subepithelial connective tissue graft (SCTG) versus xenogeneic collagen matrix (XCM) when done in association with early implant placement in the anterior maxillary esthetic region. Methods: A randomized controlled clinical trial was conducted on patients who needed to have one of their anterior maxillary teeth replaced.Two groups of twenty participants were randomly assigned:Group A received soft tissue augmentation utilizing a subepithelial connective tissue graft (SCTG) taken from the palate , while Group B received a xenogeneic collagen matrix (XCM). Both augmentation treatments were carried out eight weeks after tooth extraction, and they were done concurrently with early implant placement. The thickness of the soft tissue around the implant, the width of the keratinized mucosa are the primary parameters. “Results:”The peri-implant soft tissue thickness and keratinized tissue width were significantly improved by the subepithelial connective tissue graft and the xenogeneic collagen matrix. Soft tissue thickness were somewhat better for the SCTG group, but these changes were not statistically significant. On the other hand, patients who received XCM reported less postoperative discomfort and morbidity. Conclusion: “For soft tissue augmentation related to early implant placement in the maxillary esthetic region, the xenogeneic collagen matrix offers a viable and minimally invasive alternative to subepithelial connective tissue grafts. Even though SCTG is still the gold standard for attaining superior soft tissue than XCM, it shows similar clinical efficacy and has the benefit of lower patient morbidity. These results provide validity to the idea that, in carefully chosen situations, XCM might be a good substitute. Conclusion: Both SCTG and XCM show clinical improvement in soft tissue thickness and keratinized tissue width around early implant placement. ..
Keywords: Thin biotype, XCM, Subepithelial connective tissue graft, esthetic zone,early implant placement.
How to cite this article: Ismail MO, Abdelmonaem M, Khalil AA. Soft Tissue Augmentation by Xenogeneic Collagen Matrix Versus Subepithelial Connective Tissue Graft Around Early Implant Placement in Maxillary Esthetic Zone. Int J Drug Deliv Technol. 2025;15(4): 1994-2001, DOI: 10.25258/ijddt.15.4.52