In the present scenario drug delivery technology growing in rapid speed significantly influenced the rapid progress of drug-delivery technologies is greatly advancing the development of more precise and effective therapeutic options. Among the various delivery strategies, biocompatible drug carriers shown a pivotal model in enhancing the delivery of drug molecules. These carriers ranging from nanoparticles to liposomes, polymers, and dendrimers offer distinct advantages by ensuring the safe and controlled release of drugs, thereby improving the stability, and efficacy in treatment. The main objective of this study is to explore the current trends and innovations in biocompatible drug carriers, examining their potential to revolutionize drug delivery in both the clinical and preclinical stages. The study reviews the design principles, synthesis methods, and biocompatibility evaluations of these carriers, highlighting their application in various therapeutic areas, including cancer treatment, gene therapy, and chronic disease management. Furthermore, the study addresses the challenges and limitations associated with these systems, such as their scalability, safety, and regulatory concerns. By investigating the promising approaches and materials in the field, this work aims to contribute to the ongoing development of efficient, patient-specific in delivery that maximize therapeutic outcomes with low adverse effects. The work aims to provide a clearer understanding of how drug carriers are selected and developed to optimize therapeutic efficacy.
Keywords: Drug carriers, Transferosomes, Nanoparticles, Hydrogels, Hybrid carriers.
How to cite this article: Nirmala S, Kumari GH, From Concept to Clinic: Evolution and Impact of Carrier-Based Drug Delivery Systems. Int J Drug Deliv Technol. 2026;16(1): 139-147. DOI: 10.25258/ijddt.16.1.15