International Journal of Drug Delivery Technology
Volume 16, Issue 1

Assessment of Crinum Solapurense Leaf Extract's Analgesic and Anti-Inflammatory Properties in Mice

Dhange A.A1*, Dr. Gajeli G. B1, Dr. Ghurghure S.M2 Dr. Bobade C. D2 and Dr. Kalshetti P.D3

1D.S.T.S. Mandal's College of Pharmacy, Solapur, (Maharashtra) India
2School of Pharmacy, MIT Vishwaprayag University, Solapur
2School of Health Science and Technology, Dr. Vishwanath karad MIT World Peace University, Pune, (Maharashtra) India
3PES Modern College of Pharmacy, Nigdi, Pune, (Maharashtra) India
1*anupdhnage16@gmail.com

Received: 8th Sep, 2025; Revised: 26th Oct 2025; Accepted: 8th Nov, 2025; Available Online: 1st December, 2025

ABSTRACT

Crinum Solapurense, also referred to as "Sudershana," belongs to the Amaryllidaceae family. Currently current medications for the treatment of pain, fever, and inflammation-like disorders have a lot of negative side effects; therefore, safer medications with few or no side effects are needed. This was accomplished by screening Crinum Solapurense (Amaryllidaceae) leaves for pharmacological qualities, particularly analgesic ones, utilizing the Paw edema test method with mice and test hotplate method. When compared to the common medication, Pentazocin and Ibuprofen, the ethanolic extract of Crinum Solapurense leaves had shown substantial analgesic and anti-inflammatory action. The analgesic and anti-inflammatory properties of many medicinal plants are typically attributed to tannins, flavonoids, alkaloids, and saponins; for this reason, phytoconstituents derived from plant leaves are also being investigated. These findings might help to the activities the plant Crinum Solapurense, which is distributed in the Solapur district, is used to treat pain and related conditions.

Keywords: Crinum Solapurense, Ethanolic extract, Hot plate method, Paw edema

How to cite this article: Dhange AA, Gajeli GB, Ghurghure SM, Bobade CD and Kalshetti PD; Assessment of Crinum Solapurense Leaf Extract's Analgesic and Anti-Inflammatory Properties in Mice. Int J Drug Deliv Technol. 2026;16(1): 273-276. DOI: 10.25258/ijddt.16.1.29