Formulation and Evaluation of Sustained Release Micro Beads of Gellan Gum and Apple Peel Pectin Composite Using Aceclofenac as a Model Drug

Sitangsu Maity1* and Santosh Kumar Mahapatra2

1*Associate professor, 1Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Jharpokharia, Mayurbhanj-757086, Odisha, India
2College of Pharmaceutical Sciences, Puri-Konark Marine Drive, Baliguali, Puri-752004, Odisha
*sitangsu02@gmail.com.

Received: 28th Sep, 2025; Revised: 25th Oct 2025; Accepted: 7th Nov, 2025; Available Online: 1st December, 2025

ABSTRACT

This current communication describes the micro beads composed of apple peel pectin (APP) and gellan gum (GG) blends for sustained Aceclofenac (AC) release over a prolonged period. As a model drug candidate, AC was investigated. These AC-loaded GG-APP composite micro beads presented 46.27 ± 2.08 to 68.66 ± 2.74% entrapment efficiency and 702.84 ± 21.53 to 987.46 ± 37.57 µm average particle size. The GG-APP composite micro beads demonstrated a sustained-prolonged release over 8h.

Keywords: Aceclofenac; Apple peel pectin; Gellan gum; Micro beads; Sustained drug release

How to cite this article: Maity S, Mahapatra SK; Formulation and Evaluation of Sustained Release Micro Beads of Gellan Gum and Apple Peel Pectin Composite Using Aceclofenac as a Model Drug. Int J Drug Deliv Technol. 2026;16(1): 302-306. DOI: 10.25258/ijddt.16.1.32