International Journal of Drug Delivery Technology
Volume 16, Issue 1, 2026

A Rare Case of Acute Kidney Injury in an Adult Male: Coexistence of Acute Tubular Injury with Minimal Change Disease

Dr. Sharath Chandra Reddy Turpu1, Dr. V Padma2, Dr. Vinatha MC3, Dr. S.V. Sathyapriya4, Dr. Jagadesh M5, Dr. V. Veera Vignesh6, Dr. Bhavana Reddy7

1Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: turpusharath@gmail.com
ORCID ID: 0009-0001-6314-367X

2Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: padmaramesh86@yahoo.com
ORCID ID: 0000-0002-9938-6462

3Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: vinathamadhukar@gmail.com
ORCID ID: 0000-0003-4317-6842

4Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: svsatz1994@gmail.com
ORCID ID: 0000-0002-3397-291X

5Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: jagasri11@gmail.com
ORCID ID: 0009-0007-9483-7301

6Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: drveeravignesh@gmail.com
ORCID ID: 0009-0000-3437-1457

7Department of General Medicine, Sree Balaji Medical College, Tamil Nadu, India
Email: m.bhavanareddy12@gmail.com
ORCID ID: 0009-0004-3910-9713

Received: 28th Aug, 2025; Revised: 25th Nov, 2025; Accepted: 22nd Dec, 2025; Available Online: 18th Jan, 2026


ABSTRACT

Minimal Change Disease (MCD) is an uncommon cause of nephrotic syndrome in adults and rarely presents as acute kidney injury (AKI). This case report describes a 58-year-old male who developed AKI in the context of MCD, confirmed through renal biopsy. His clinical course was marked by oliguric renal failure necessitating dialysis, and subsequent recovery was achieved through high-dose corticosteroids, immunosuppression with mycophenolate mofetil (MMF), and supportive care. This case highlights the critical role of renal biopsy in diagnosing atypical presentations of AKI in adults and underscores the therapeutic benefits of early immunosuppressive treatment.

Keywords: N/A.

How to cite this article: Turpu SCR, Padma V, Vinatha MC, Sathyapriya SV, Jagadesh M, VeeraVignesh V, Reddy B. A Rare Case of Acute Kidney Injury in an Adult Male: Coexistence of Acute Tubular Injury with Minimal Change Disease. Int J Drug Deliv Technol. 2026;16(1): 513-515; DOI: 10.25258/ijddt.16.1.55

Source of support: Nil.

Conflict of interest: None