1Doctoral Program in Medical Science, Faculty of Medicine, Universitas Airlangga, Indonesia
2Department of Medical Microbiology, Faculty of Medicine, Universitas Airlangga, Indonesia
Corresponding Author Email: eddy-b-w@fk.unair.ac.id
3Department of Anatomy, Histology and Pharmacology, Faculty of Medicine, Universitas Airlangga, Indonesia
Received: 14th Sep, 2025; Revised: 25th Oct, 2025; Accepted: 16th Nov, 2025; Available Online: 1st December, 2025
Ulva lactuca algae are one type of green algae (Chlorophyta) that contains many important bioactive compounds such as sources of antioxidants, namely flavonoids and phenols, as well as steroids that have the potential as anti-infertility. Sources of antioxidants in the Ulva lactuca algae originating from the Gondol Beach of Bali were observed through laboratory testing through phytochemical screening and soxhlet extraction with 96% ethanol. This study aimed to identify and analyze the bioactive compounds in the algae Ulva lactuca as an antioxidant and anti-infertility effect. The research used experimental laboratory and computational methods. The results showed that the Ulva lactuca through the TLC test contained flavonoid, triterpenoid, and steroid bioactive compounds. Through GC-MS test, it contained a sterol product, namely 29-isofucosterol, with a normalized value of 5.6%. Examination using the bioinformatic method metabolites in Ulva lactuca can bind to proteins as well as antioxidant enzymes and sex steroid hormones in women. Ulva lactuca has the potential as an antioxidant and anti-infertility that works synergistically on the reproductive organs. Thus, it can be used for complementary therapy for disorders of the female reproductive system with fertility problems, which has minimal risks and side effects.
Keywords: Antioxidant-antiinfertility; Bioactive compounds; Ulva lactuca; TLC and GC-MS.
How to cite this article: Arini LA, Wasito EB, Mustika A. Analysis of the Role of Ulva Lactuca Bioactive Compounds from Gondol Beach Bali as an Antioxidant and Anti-Infertility. Int J Drug Deliv Technol. 2026;16(1): 583-638; DOI: 10.25258/ijddt.16.1.65
Source of support: Nil.
Conflict of interest: None