1*Research Scholar, Faculty of Pharmacy, Lords University, Alwar, 301028, Rajasthan, India. Email: ompharma096@gmail.com
2Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Lords University, Alwar, 301028, Rajasthan, India. Email: mittalnitin1901@gmail.com
Mesoporous silica nanoparticles are seen as it is chemically stable and also showing thermal stability having very good porosity and morphological characteristic property. These particles having very good internal and external surfaces so that they can function with both the molecule either it is organic or inorganic. Silica is also very less toxic in nature so it is observed very best carrier for the nanotherapeutic delivery of the drugs to the body. The preparation of the silica nanoparticle was done with the Methanol (MeOH), Distilled water and Tetraethyl orthosilicate (TEOS) within the existence sodium hydroxide as catalyst and temperature at 80°C. Characterization through X-ray diffraction (XRD), in vitro release study, haemolytic study and also cell line studies. Silica is good nanocarrier because of the no changes in the drug characteristics either structurally or chemically. It is showing desirable effect after release of the drug. The formulation shows very good effect of solubilisation of the non-hygroscopic nature of the drug Etoposide (ETP). The formulation shows good performance for the targeting delivery and also low toxicity profile with very higher rate of stability within the nano formulation.
Keywords: MCM-41, Mesoporous Silica Nanoparticles, Etoposide, Targeted Drug Delivery, Lung Cancer, Nanotherapy
How to cite this article: Yadav OP, Mittal N. Targeted Lung Cancer Treatment Using Etoposide-Conjugated MCM-41 Nanoparticles. Int J Drug Deliv Technol. 2026;16(10s): 838-841; DOI: 10.25258/ijddt.16.10s.98
Source of support: Nil.
Conflict of interest: None