1Department of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.
Corresponding Author: Dr. Tanu Sahney, MDS, Associate Professor, Department of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India. E-mail: tanu.sahney910@gmail.com
Background: Throughout the years, various management approaches have been explored to address dentine hypersensitivity. Recently, a tricalcium silicate-based cement has gained popularity as a "Dentine substitute" due to its mineralization properties, sealing dentinal tubules, and preserving pulp vitality. This potential can be harnessed for obliterating the tubular structure in dentine for managing dentine hypersensitivity. This comparative study investigates the efficacy of 810 nm diode laser, Novamin, and Active Biosilicate Technology on dentine tubule occlusion.
Methods: This in vitro, single-blinded research was conducted on thirty prepared dentine sections. The samples were allocated in three treatment groups: Group A - 810nm diode laser; Group B – Novamin paste; and Group C – Active Biosilicate Technology. The samples were observed for 'Full Open' and 'Partial Open' dentinal tubules using a Scanning Electron Microscope (SEM) combined with energy-dispersive X-ray (EDX) spectroscopy.
Results: Active Biosilicate Technology showed the fewest fully and partially open tubules at all magnifications. ANOVA revealed significant intergroup differences at ×5,000 (F = 7.56, p = 0.011) and ×10,000 (F = 8.63, p = 0.001). Tukey's test confirmed greater tubule occlusion in Groups B and C than in Group A (p < 0.05), with no difference between B and C. EDX showed higher calcium and phosphorus deposition in Group C.
Conclusion: Active Biosilicate technology demonstrated the most effective and consistent dentine tubule occlusion, followed by Novamin and diode laser. The superior sealing ability of Active Biosilicate Technology suggests its strong potential as a desensitizing agent in clinical practice, offering a reliable option for the long-term management of dentine hypersensitivity.
Keywords: Dentin Sensitivity, Tooth Demineralization, Dentin Desensitizing Agents, Lasers, Microscopy.
How to cite this article: Tiwari S, Srivastava V, Srivastava A, Meenawat A, Khan YS, Sahney T. Comparative Evaluation of Diode Laser, Novamin, and Active Biosilicate Technology for Dentinal Tubule Occlusion: An In Vitro Scanning Electron Microscope (SEM) and Energy Dispersive X-Ray Analysis (EDX) Study. Int J Drug Deliv Technol. 2026;16(11s): 485-491. DOI: 10.25258/ijddt.16.11s.48
Source of support: Nil.
Conflict of interest: None