A Prospective Study Of Individualized Homoeopathic Medical Expulsive Therapy In Uncomplicated Ureteric Calculi

K Gayathri^1*, Mrinal A Nerlekar²

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ABSTRACT

Background: Ureteric Calculi: When Concentrations Of Stone Salts In The Urine Surpass The Limit Of Metastability, Stones Develop In The System. The Common Causes Of This Are Either Low Urine Volume Leading To Overly Concentrated Urine Or Excessive Excretion Of One Or More Stone Components. There Are Five Sites Of Anatomical Constrictions In Ureters, Where The Stone May Be Halted. 1. Pelvi Ureteral Junction 2. Vesico Ureteric Junction 3. Crossing Of Illiac Artery 4. Juxtaposition Of Broad Ligament/Vas Deferens 5. Ureteral Orifice Inside The Bladder Wall. Clinical Features: Hematuria, Radiation To The Testis, And Sudden, Intense Pain That Makes It Difficult To Pass Urine Are All Signs Of Ureteric Colic. Acute Colicky Pain Is A Symptom Of Intermittent Ureteric Blockage Caused By A Stone Traveling Down The Ureter. Infection Is Indicated By Fever, Urgency, Frequency, And Strangulation Along With Ureterovesical Junction Stones. Complete Anuria And A Sharp Decline In Renal Function Can Result From Bilateral Or Single Kidney Ureteric Stones. Ureteropelvic Stone In Upper Left- Significant Pelvic Distension And Capsular Discomfort At The Costovertebral Angle. Mid-Ureteral Stone In Upper Right- Greater Discomfort In The Lower Quadrants Of The Abdomen. Lower Left - Stones In The Lower Ureters. Bladder Symptoms- Burning, Urgency, Frequency, Pain May Be Referred To Penis When The Stone Gets Close To The Bladder.

Methods: This Is A Non-Randomized Interventional Clinical Trial Carried Out At Bharati Vidyapeeth (Deemed To Be University) Homoeopathic College & Research Centre, Pune, In The Outpatient Department. A Total Of 32 Patients Were Analyzed. Case Definition: Cases Pre-Diagnosed /Newly Diagnosed With Ureteric Calculi Less Than Or Equal To 7mm Of Age Group 18-60 Years And Justifying All Inclusion And Exclusion Criteria Were Considered. Out Of 32 Cases, 2 Dropped Out And The Rest Completed Their Follow-Ups. Every Visit, Symptomatology And Generals Of Patient Along With Pain Status Using Vas Score Were Recorded With Study Criteria Investigations Done Before And After The Study.

Results: A Total Of Thirty-Two Cases Were Included In The Data Analysis. The Hypothesis That The Average Period For Stone Ejection Is 30 Days Was Assessed Using The T-Test Where The P-Value Is 0.672 And The Test Statistic Is T = -0.43. Statistical Non-Significant In This Case Is A P-Value Of Less Than 0.05. The Average Period For Stone Expulsion With Individualized Homeopathic Medications Is 30 Days, Based On Statistical Analysis Of 28 Patients. Two Participants Have Withdrawn From The Research. Despite Being Unable To Remove The Stone, Two Patients Reported That The Size Of The Stone Decreased. Descriptive Statistics And The Wilcoxon Signed-Rank Test Were Employed To Assess Pain Scores (Vas) Before And After Treatment For Ureteral Stone Management Which Revealed A Significant Reduction In Patients' Median Pain Score (Iqr) Priorly 4, Which Decreased To 2 Following Treatment. Similarly, The Mean ± Sd Pain Score Dropped From 4.31 ± 1.03 Before Treatment To 2.28 ± 0.63 After Treatment, Indicating A Substantial Improvement In Patient-Reported Pain Levels. This Demonstrates Unequivocally That Individualized Homeopathic Medicines Can Be Used To Treat Ureteric Calculi.

Keywords: Ureteric calculi, Medical expulsive therapy, Complementary and alternative medicine, Urolithiasis.

How to cite this article: Gayathri K, Nerlekar MA.., A Prospective Study Of Individualized Homoeopathic Medical Expulsive Therapy In Uncomplicated Ureteric Calculi..Int J Drug Deliv Technol. 2026; 16(11s): 805-818; DOI: 10.25258/ijddt.16.11s.82

Source of support: Nil.

Conflict of interest: None