Volume 16, Issue 12s, 2026 | PG 121-129
A Comprehensive Strategy For Rodent Control With Antifertility Attributes Using Triptolide
Parul Dhar1*, Preeti Kalia2, Shyna Bhalla3, Kritika Saini4, Anita Sharma5, Aditi Bisht6
1University School of Life Sciences, Rayat Bahra University, Mohali, Punjab-140103, India
2Department of Zoology, Goswami Ganesh Dutta Sanatan Dharma College, Chandigarh-160032, India
3University School of Life Sciences, Rayat Bahra University, Mohali, Punjab-140103, India
4University School of Life Sciences, Rayat Bahra University, Mohali, Punjab-140103, India
5University School of Life Sciences, Rayat Bahra University, Mohali, Punjab-140103, India
6Department of Biosciences (UIBT), Chandigarh University, Mohali, Punjab-140413, India
*Corresponding Author: Parul Dhar, University School of Life Sciences, Rayat Bahra University, Mohali, Punjab-140103, India
Graphical abstract
ABSTRACT
Rodents, as pests, cause tremendous negative impacts on the global economy, food resources, and human health. The conventional trapping methods are appropriate only for small scale which specifically can address rat problems at the domestic settings, however they don't show propitious results in agricultural fields and commercial scale. Rodenticides play an important role in rodent pest management against Rattus sp., Mus sp., Bandicota sp., and other field rats but alone they are not that much effective. To stop rodent nuisance effectively, a better-opted approach has been the development of integrated control programs that includes mechanical, chemical, and biological strategies. Chemical control like use of rodenticides when integrated with antifertility drugs is anticipated to enhance the effective control over rodents, and one of such antifertility plant-based substance is triptolide which has highly promising results. Triptolide is a compound derived from T. wilfordii, a perennial Chinese twining vine and has shown substantial promise in tackling the rodent infestation. The present review highlights the scope of antifertility properties of triptolide, supported from earlier investigations in managing rodent problems. The integration of reproductive control techniques using triptolide along with rodenticide offers very promising and long-lasting approach for the management of rodents as pests.
Keywords: Rodents, Pests, Rodenticides, Antifertility agent, Triptolide.
How to cite this article: Dhar P, Kalia P, Bhalla S, Saini K, Sharma A, Bisht A. A Comprehensive Strategy for Rodent Control with Antifertility Attributes using Triptolide. Int J Drug Deliv Technol. 2026;16(12s): 121-129. DOI: 10.25258/ijddt.16.12s.13
Source of support: Nil.
Conflict of interest: None