1Assistant Professor, Department of Dental Surgery, Government Medical College and Hospital, Khammam, Telangana. Email: drlavnaya.3006@gmail.com
2Associate Professor, Department of Dental Surgery, Government Medical College and Hospital, Khammam, Telangana. Email: drstranipedo@gmail.com
3Assistant Professor, Department of Dental Surgery, Government Medical College and Hospital, Kamareddy, Telangana. Email: anilmahi12@gmail.com
4Professor, Department of Pedodontics and Preventive Dentistry, NSVK, Sri Venkateswara Dental College and Hospital, Bangalore. Email: kamalakiran@gmail.com
5Senior Lecturer, Pediatric and Preventive Dentistry, The Oxford Dental College, Hongasandra, Bangalore. Email: rithuparnafeb96@gmail.com
6Pediatric and Preventive Dentistry, The Oxford Dental College, Hongasandra, Bangalore. Email: anushreesshenoy02@gmail.com
Corresponding Author: Dr. Anushree S Shenoy, Pediatric and Preventive Dentistry, The Oxford Dental College, Hongasandra, Bangalore. Email: anushreesshenoy02@gmail.com
Aim: To compare clinical and microbiological effects among individuals with chronic periodontitis and well-controlled type II diabetes after treatment with scaling and root planing alone, scaling and root planing associated with photodynamic therapy (PDT), or scaling and root planing in combination with low-level laser therapy (LLLT).
Objectives: 1. To assess the Modified Sulcular Bleeding Index (mSBI), Plaque Index (PI) and Probing Pocket Depth (PPD) from baseline till 45 days follow up to detect changes. 2. To quantify colony-forming units (CFU) in subgingival plaque at baseline and 45 days after treatment.
Settings and Design: Thirty patients (30–50 years old) with chronic periodontitis and type II diabetes (HbA1c 6–7%) were recruited in a parallel-arm, randomized clinical trial and microbiological study. Subjects were randomly allocated in equal numbers to three treatment groups.
Materials and Methods: After ethical clearance, participants underwent full-mouth SRP. Group II also received LLLT, group III was treated with ICG-PDT. PI, mSBI and PPD were recorded at baseline and 45 days and subgingival samples were taken for CFU. Descriptive statistics was expressed as mean ± SD. Intragroup comparisons were performed with the paired t-test and intergroup comparisons with unpaired Student's t-tests, where P< 0.05 was regarded as significant.
Results: There was a meaningful improvement from baseline to day 45 in all three groups, both in clinical indices and microbial counts (P <0.001). Between-group comparisons showed that adding light-based therapy to SRP significantly enhanced outcomes. The SRP+PDT group achieved the largest reductions in plaque index and bleeding index, while the SRP+LLLT group also outperformed SRP alone. Both adjunctive groups had significantly lower PPD, PI, and mSBI than the SRP-only group (P<0.05). The highest level of bacterial reduction was observed in the SRP+PDT group.
Conclusion: Adjunctive photodynamic or low-level laser therapy with SRP produced significantly greater clinical improvements than SRP alone in diabetic patients with chronic periodontitis. Both light-based treatments enhanced healing, suggesting their potential value as supplements to standard periodontal therapy.
Keywords: chronic periodontitis; diabetic; photodynamic therapy; low-level laser therapy; colony-forming units
How to cite this article: Boyeena L, Rani ST, Kumar A, Kamala BK, Shaji R, Shenoy AS, Comparative evaluation of efficacy of SRP alone Vs PDT, LLLT after SRP in the management of diabetic patients with Chronic Periodontitis - A Clinical trial and Microbiological Assay..Int J Drug Deliv Technol. 2026;16(12s): 392-397. DOI: 10.25258/ijddt.16.12s.44
Source of support: Nil.
Conflict of interest: None