International Journal of Drug Delivery Technology
Volume 16, Issue 12s, 2026

A RP-HPLC Method Development, Validation And Estimation Of Clarithromycin

J. Sai Chandra1, Davuluri Yogeshwar Rao2, Islavathu Hatti3, K. Aruna Kumari4, V.B.V.S. Rama Krishna5, K. A. Emmanuel6, R. Jalababu7, Anitha Nallamothu8, K.V.L.N. Murthy9

1Dept of Chemistry, JNTUH University College of Engineering Sultanpur, Telangana, India - 502273

2Assistant Professor, Dept. of Chemistry, Krishnaveni Degree College, Narasaraopet, Andhra Pradesh, India - 522601

3Lecturer in Chemistry, Jagarlamudi Kuppuswamy Choudary Autonomous College, Guntur, Andhra Pradesh, India - 522006

4Assistant Professor, Dept. of Chemistry, Dhanekula Institute of Engineering & Technology (Autonomous), Vijayawada, Andhra Pradesh, India - 521139

5Lecturer in Chemistry, K.R.K. Govt. Degree College, Bapatla, Andhra Pradesh, India - 522001

6Professor, Dept. of Chemistry, Y. V. N. R. Government Degree College, Eluru District, Andhra Pradesh, India - 534001

7Lecturer in Chemistry, Y. V. N. R. Government Degree College, Andhra Pradesh, India - 534001

8Assistant Professor, UCEN-JNTUK Narasaraopet, Andhra Pradesh, India - 522601

9Dept. of Chemistry, S.V.R. Degree College, Macherla, Andhra Pradesh, India - 522426


ABSTRACT

Objective: New RP-HPLC method was developed for the simultaneous estimation of clarithromycin. RP-HPLC method was a simple, reliable and acceptable and it confirmed that method is suitable for the intended use for routine quality control and assay of drugs. This method is successfully applied for the determination of commercial dosage form preparation.

Validation: This method is validated as per ICH (International conference on harmonization) guidelines.

Keywords: RP-HPLC, Clarithromycin, Method development, Method validation.

How to cite this article: Sai Chandra J, Yogeshwar Rao D, Hatti I, Aruna Kumari K, Rama Krishna VBVS, Emmanuel KA, Jalababu R, Nallamothu A, Murthy KVLN. A RP-HPLC Method Development, Validation and Estimation of Clarithromycin. Int J Drug Deliv Technol. 2026;16(12s): 652-657. DOI: 10.25258/ijddt.16.12s.77

Source of support: Nil.

Conflict of interest: None