1,2,3,4Taywade College of Pharmacy Koradi, Nagpur, Maharashtra 441111
5Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Dr. M.G.R Educational and Research Institute, Chennai, Tamil Nadu - 600077, India
6KJEI's Trinity College of Pharmacy, Pune, Maharashtra - 411048
7Department of Pharmacy, Government Polytechnic for Women, Srikakulam, Gujarathipeta, Srikakulam, Andhra Pradesh, India – 532005
8Jagran School of Pharmacy, Bhopal M.P - 462044
9Himalayan Institute of Pharmacy Kala Amb, Sirmour Himachal Pradesh - 173030
*Corresponding Author: Geeta N. Lodhi, Taywade College of Pharmacy Koradi, Nagpur, Maharashtra 441111. Email: geetalodhi26@gmail.com
Emails: vikrantchilate15@gmail.com, k.machewar@tcop.edu.in, priya.thakre13@gmail.com, senthilbssk@gmail.com, bmf.phd123@gmail.com, kondavvskrishna@gmail.com, aliasra0388@gmail.com, pmvcp@rediffmail.com
Objective: The main goal was to assess possible memory-enhancing effects of Withania somnifera root extract on Wistar rats.
Materials and Methods: Extract of Withania somnifera roots evaluated for memory-enhancement by Morris Water Maze (MWM) and Elevated Plus Maze (EPM). Here, Parameter examined was transfer latency (TL).
Results: There was dose-dependent decline in TL when Withania somnifera root extract was administered, as compared to the control.
Conclusion: The observed dose-dependent reduction in transfer latency provides compelling evidence of the extract's potential in countering neurodegeneration and affirming its nootropic capabilities.
Key words: Withania somnifera roots, EPM, MWM, Memory, Learning
How to cite this article: Lodhi GN, Chilate VV, Machewar KA, Thakre PD, Kumar PS, Firake BM, Krishna KVVS, Ali A, Chauhan J. Neuroprotective and Memory Enhancing Effects of Withania somnifera Extract in Experimental Models. Int J Drug Deliv Technol. 2026;16(12s): 707-714. DOI: 10.25258/ijddt.16.12s.84
Source of support: Nil.
Conflict of interest: None