1Final Year Student, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Karad
2Assistant Professor, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Karad
Corresponding Author: Purva Ravindra Kambale
Background: Chemotherapy and radiation therapy, two primary approaches to cancer treatment, can result in dose-dependent damage to body tissues, leading to complications like fatigue, muscle weakness, neuropathy, and fibrosis. These side effects may interfere with daily tasks, mobility, and overall well-being. Physiotherapy provides essential support in managing these complications through personalized rehabilitation strategies, including mobility enhancement, pain management, strengthening exercises, and balance training. Early physiotherapeutic intervention not only aids recovery but also prevents further complications and supports mental health. A clear understanding of how treatment doses affect tissues allows physiotherapists to develop more targeted and effective recovery plans.
Methods: This observational study assessed dose-related skin changes in cancer survivors who underwent chemotherapy and radiation. A custom-designed questionnaire was used to gather data from 50 participants. Ethical approval and informed consent were obtained prior to data collection.
Results: Participants, mostly in Stage 2 cancer, had undergone chemotherapy or radiation therapy. A significant number received high-dose treatments, with 88% experiencing skin problems such as dryness, redness, and itching—primarily after completing therapy. These symptoms mainly affected the face, neck, and chest, and disrupted daily activities for 90% of respondents. Many reported emotional challenges. Over 80% sought medical treatment, and 67% were referred to physiotherapy, which commonly involved skin care advice and mobility exercises. While many found these interventions moderately effective, a large number desired additional support.
Conclusion: Though essential in cancer care, chemotherapy and radiation can cause dose-related tissue reactions with both short- and long-term consequences. Gaining insights into these effects is crucial for improving therapeutic approaches. New techniques, such as proton therapy and precision drug delivery, are showing potential in reducing adverse reactions. Tailoring treatments to balance efficacy and long-term outcomes is key to improving survivors' quality of life.
Keywords: Cancer, Chemotherapy, Radiation therapy, Post-therapy, Topical Change
How to cite this article: Kambale PR, Patil P. Analysis of Dose Specific Topical Changes in Post Chemotherapy and Radiation Therapy in Cancer Survivors. Int J Drug Deliv Technol. 2026;16(13s): 902-908. DOI: 10.25258/ijddt.16.13s.101.
Source of support: Nil.
Conflict of interest: None