1Research Scholar, Department of School of Pharmaceutical Sciences, CSJMU Kanpur. Email: phd202300001870@csjmu.ac.in
2Associate Professor, Department of School of Pharmaceutical Sciences, CSJMU Kanpur
3Sandip Patil
4*Shashi Kiran Misra (Corresponding Author). Email: shashikmishra@csjmu.ac.in
Background: Because of PVA (CAS No. 9002-89-5) introduction and possible uses in a variety of fields, different polymers with multifunctional qualities are attractive. PVA and other synthetic polymers are highly esteemed as biodegradable, useful materials with biocompatibility properties. PVA has been considered a promising material for a variety of applications for over fifty years.
Methods: This article presents a set of experiments, 10% w/v Polyvinyl Alcohol (Industrial grade) was found to be adequate for formation of smooth, defect free, and regular fibers. It also discusses the many methods used to characterize the polymer. The production of smooth, nano-range, mesh-like structures with distinct pockets within their structure was enthusiastically recognized by scanning electron microscopy (SEM). X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) confirmed the PVA scaffolds' polymer production and improved thermal behavior.
Results: This review presents PVA nanofiber preparations, optimizations, characterizations, and applications. Due to the polymer blend's somewhat improved permeability, the nanofibers' high swelling ability and hydrophilicity were attained. This lowers the crucial level for the creation of a nanofibrous scaffold, which is used to grapheme-linezolid composite drug delivery for stop fungal infections and an awesome treatment in burn wounds.
Conclusion: Concluded by announcing improved nanofibers and putting out more persuasive dressing materials for a common burn wound infection regimen. Recent applications of grapheme-linezolid composite drug delivery for PVA in biomaterials have also been highlighted in the paper.
Keywords: PVA, Fabrication, Characterization, Optimization of Fabrication, Graphene.
How to cite this article: Kumar R, Kumar A, Patil S, Misra SK. Fabrication and Characterization of Graphene and Linezolid Composite Loaded Scaffolds for Awesome Drug Delivery at Site of Burn Wounds. Int J Drug Deliv Technol. 2026;16(13s): 259-266. DOI: 10.25258/ijddt.16.13s.28
Source of support: Nil.
Conflict of interest: None