1*Department of Pharmacognosy, Pacific Academy of Higher Education & Research University, Udaipur, Rajasthan, India.
2Department of Pharmacognosy, Pacific Academy of Higher Education & Research University, Udaipur, Rajasthan, India.
Background: In the present work, polyherbal silver nanoparticles were synthesized using the aqueous extracts of Tinospora cordifolia and Ficus religiosa through a green synthesis approach. The plant phytoconstituent acted as a natural reducing and stabilizing agent, facilitating the formation of silver nanoparticles. These polyherbal AgNPs are incorporated into a transdermal patch formulation to develop a novel anti-microbial drug delivery system.
Methods: The prepared patches were evaluated for physical properties and antibacterial activity. Characterization studies confirm the successful synthesis of stable nanoparticles with suitable size and morphology.
Results: The silver nanoparticle-loaded patches exhibited significant antibacterial activity against both Gram-positive and Gram-negative bacteria, demonstrating their potential application in the controlled and sustainable management of bacterial infection.
Keyword: Tinospora cordifolia, Ficus religiosa, green synthesis, polyherbal AgNPs, antibacterial activity, transdermal patches
How to cite this article: Sharad KR, Khathuriya R. Formulations and Characterization of Polyherbal Silver Nanoparticles for Assessment of its Anti-Bacterial Activity. Int J Drug Deliv Technol. 2026;16(13s): 326-335. DOI: 10.25258/ijddt.16.13s.35
Source of support: Nil.
Conflict of interest: None