1*Assistant Professor, School of Agricultural Science, Renaissance University, Indore
Global agriculture is under increasing pressure from climate change, resource limitations, and the need to sustainably feed a growing population. Plant biotechnology is undergoing a fundamental transition from single-trait genetic modifications to systems-level and precision-driven biological redesign. This review synthesizes major high-impact advances in plant biotechnology over the past five years, with a focus on technologies that integrate precision engineering with sustainability. Recent progress in genome editing has extended beyond conventional CRISPR/Cas9 systems to advanced platforms such as Base Editors and Prime Editors, enabling precise nucleotide modifications and gene replacements critical for improving complex quantitative traits. These genome engineering tools are complemented by plant synthetic biology approaches, which facilitate the rational design of genetic circuits and metabolic pathways for enhanced stress resilience and molecular farming applications, including the production of high-value bioproducts. The integration of multi-omics technologies with artificial intelligence and machine learning has further accelerated data-driven target identification, functional gene discovery, and predictive breeding strategies. In parallel, emerging approaches such as plant microbiome engineering and nano-biotechnology are contributing to sustainable agriculture by improving nutrient and water use efficiency and enabling targeted delivery of genetic materials. Although challenges related to transformation efficiency, scalability, and regulatory frameworks remain, the convergence of these emerging biotechnologies represents a powerful and integrated toolkit. Collectively, these innovations provide a strong foundation for developing climate-resilient, high-yielding, and environmentally sustainable crop varieties essential for global food security.
Keywords: Genome Editing, CRISPR/Cas, Synthetic Biology, Plant Microbiome, Metabolic Engineering, Abiotic Stress, Climate Change, Sustainable Agriculture.
How to cite this article: Patidar S. Precision and Sustainability: Emerging Technologies Driving the Next Generation of Plant Biotechnology for a Climate-Resilient Future. Int J Drug Deliv Technol. 2026;16(15s): 264-269. DOI: 10.25258/ijddt.16.15s.33
Source of support: Nil.
Conflict of interest: None