1Trainee of Head and Neck Surgery, Airlangga University, Soetomo General Hospital, Surabaya, Indonesia.
2Staff of Department of Head and Neck Surgery, Airlangga University, Soetomo General Hospital, Surabaya, Indonesia.
Parathyroid carcinoma (PC), an extremely rare endocrine malignancy, was found to coexist synchronously with papillary thyroid carcinoma (PTC) in a 23-year-old male, presenting a unique and complex case. The patient displayed signs of severe primary hyperparathyroidism, including weakness, bone pain, and weight loss, supported by severe hypercalcemia (Ca 16.8 mg/dL) and markedly elevated PTH (2662 pg/mL), with multiple lytic bone lesions. Diagnostic workup revealed multiple lytic bone lesions and a synchronous papillary thyroid carcinoma (PTC) confirmed by FNAB. The patient underwent en bloc resection including parathyroidectomy and hemithyroidectomy. Postoperatively, calcium and PTH levels significantly decreased. Histopathology confirmed an atypical parathyroid tumor with lymphovascular invasion. This case emphasizes the complexity of managing severe hyperparathyroidism complicated by coexisting PTC in a young patient.
Keywords: Parathyroid carcinoma; Atypical parathyroid tumor; Hypercalcemia; Papillary thyroid carcinoma; Skeletal involvement.
How to cite this article: Melatunan LA, Wibowo MD. A Rare Atypical Parathyroid Tumor In Young Adult Man : A Diagnostic Challenge. Int J Drug Deliv Technol. 2026;16(15s): 440-442. DOI: 10.25258/ijddt.16.15s.52
Source of support: Nil.
Conflict of interest: None