1*Department of Pharmacognosy, Smt. Sharadchandrika Suresh Patil College of Pharmacy, Chopda, Maharashtra, India
The given work was done to perform an analytical review and phytochemical standardization of the solvent-based and chromatographic Syzygium cumini fruit extracts. The extraction of fruits using different solvents of varying polarity was repeated in order to get different extract fractions. To measure the changes in phytochemical distribution, extracts were analysed in terms of percentage yield, the preliminary phytochemical composition, total phenolic content (TPC) and total flavonoid content (TFC). Quantitative estimation indicated that polar extracts and more so ethanol and aqueous portions had very high contents of phenolics and flavonoids, thus this showed that polyphenolic constituents were extracted successfully. It was observed that phenolics, flavonoids, tannins or saponins were the most abundant phytochemicals in polar extracts with little or no phytochemicals in non-polar extracts. The HPTLC/HPLC-based chromatographic fingerprinting was able to produce repeatable chemical profiles and prepare key marker compounds identifiable and quantifiable. Major phenolic markers included gallic acid, ellagic acid and anthocyanins where anthocyanins was the most abundant in the quantified compounds. Combination of solvent-based extraction, spectrophotometric estimation, and chromatographic fingerprinting has provided a dependable analysis system of quality analysis of Syzygium cumini fruit extracts. Altogether, the results emphasize the significance of the standardization of phytochemicals through the usage of markers to guarantee the quality, consistency, and reproducibility of herbal raw materials and formulations.
Keywords: Syzygium cumini; phytochemical standardization; total phenolic content; total flavonoid content; chromatographic fingerprinting.
How to cite this article: Usman MRM, Bhalchandra PH. Comprehensive Phytochemical Profiling and Chromatographic Standardization of Sequential Solvent Extracts of Syzygium cumini Fruits. Int J Drug Deliv Technol. 2026;16(15s): 890-894. DOI: 10.25258/ijddt.16.15s.99
Source of support: Nil.
Conflict of interest: None