1* Resident Neurology, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: farhan_t_butt@hotmail.com | Phone: 0333 6477400 (Corresponding Author)
2 Consultant Neurologist, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: drwaswal1@gmail.com | Phone: 03203499000
3 Resident Neurology, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: sahalarsh@gmail.com | Phone: 03149474586
4 Consultant Neurologist, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: fawad2168@gmail.com | Phone: 0344-7677382
5 Resident Neurology, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: fizzakhurram.fk@gmail.com | Phone: 03349990460
6 Resident Neurology, Department of Neurology, PEMH Rawalpindi, Pakistan. Email: drhameed0332@gmail.com | Phone: 03449399786
Objective
To determine the frequency of MASLD in patients presenting with ischemic stroke at Tertiary Care Hospital.
Study Design
Descriptive cross-sectional study.
Place and Duration of the Study
Neurology Department, Pak Emirates Military Hospital Rawalpindi, from 23-10-2025 to 23-01-2026.
Methodology
This study was conducted after taking ethical approval from IRB. A total of 92 patients presenting with ischemic stroke were included in the study after taking written informed consent. MASLD was assessed by abdominal ultrasound and measurement of ALT and AST levels. Data were collected on predesigned proforma. Data analysis was done using SPSS v26, and p-value ≤0.05 was considered statistically significant.
Results
A total of 92 patients with ischemic stroke were included (mean age 51.3 ± 5.9 years; 63% male), MASLD was found in 24% patients. MASLD was observed in 17.2% males and 35.3% females (p = 0.05). MASLD prevalence was higher in patients with dyslipidemia (39.5% vs 13.0%, p = 0.003), hypertension (37.1% vs 15.8%, p = 0.020), diabetes (34.1% vs 14.6%, p = 0.028), and BMI >25 kg/m² (70.0% vs 11.1%, p < 0.001). No significant association was found with age (p = 0.528).
Conclusion
The results of study suggest that, MASLD is common among patients with ischemic stroke and is strongly associated with metabolic risk factors, and female gender. These findings highlight the significance of early identification, monitoring, and management of MASLD to potentially reduce the burden of stroke.
Keywords: MASLD, Ischemic stroke, Tertiary Care Hospital
How to cite this article: Tahir F, Muhammad W W, Arshad S, Ahmad F, Khurram F, Rehman H U. Frequency of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) in Patients Presenting with Ischemic Stroke at Tertiary Care Hospital. Int J Drug Deliv Technol. 2026;16(19s): 402-406. DOI: 10.25258/ijddt.16.19s.48
Source of support: Nil.
Conflict of interest: None