International Journal of Drug Delivery Technology
Volume 16, Issue 1s

Advances in Nanocarriers for Targeted Drug Delivery: A Review

Gajanan Chavan 1, Ashita Anand2, Rakshita Garg 3, Dr. Dilip Hinge4, Dr. Amol Shete5

1Assistant Professor, Department of E&TC Engineering, Vishwakarma Institute of Technology, Pune, Maharashtra, 411037 Email ID : gajanan.chavan@vit.edu
2Assistant Professor,School of Allied Health Sciences,Noida International University,Uttar Pradesh 203201,India. Email ID : ashita.anand@niu.edu.in
3Assistant Professor,Department of Pharmacology,  Arya College of Pharmacy,Jaipur, Rajasthan, India. Email ID : rakshita.arya@aryajaipur.com
4Assistant Professor, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth “Deemed to be University”, Taluka-Karad, Dist-Satara, Pin-415 539, Maharashtra, India Email ID : ddhinge@gmail.com
5Asso. Professor, Dept. of Pharmaceutics, Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth “Deemed to be University”, Taluka-Karad, Dist-Satara, Pin-415 539, Maharashtra, India Email ID : amol.shete@rediffmail.com


ABSTRACT

Customised drug delivery systems (TDDS) are more significant in modern medicine, so new nanocarrier technologies have been developed. superior absorption, controlled release, and the ability to target certain cells or locations make nanocarriers far superior than conventional methods of delivering medications. Thanks to these developments in nanocarriers, many illness therapies are today more effective. These include of infections, neurological issues, and cancer. The present development in nanocarriers for particular medication delivery is discussed in this work. It mostly addresses the several types of nanocarriers, their functionalisation techniques, and their applications in medicine. Most well-known forms of nanocarriers presently include liposomes, polymeric nanoparticles, dendrimers, and solid lipid nanoparticles. Every one of them has unique characteristics that target particular tissues, speed up the release of the medication, and provide stability. Targeting receptors that are overexpressed on ill cells is made feasible by functionalising techniques like ligand, antibody, or peptide addition to the surface. This makes medicine distribution far more exact. Moreover, overcoming natural limitations such as the blood-brain barrier has made it feasible to address central nervous system issues in fresh approaches. The paper also addresses the challenges like stability, biocompatibility, and scalability that arise when nanocarrier systems are applied in the clinic. More and more research indicates, despite these challenges, nanocarriers are more personalised and effective as they may totally alter the way medications are administered. Furthermore, recent advancements in nanocarrier-based therapeutics show promise in clinical trials and suggest that they might be able to raise patient outcomes. This study emphasises the requirement of continuous research in this field and handling of technical and legal issues that must be resolved before nanocarriers for particular medication transportation may completely display their advantages..

Keywords: Nanocarriers, Targeted drug delivery, Liposomes, Polymeric nanoparticles, Functionalization

How to cite this article: Chavan G, Anand A, Garg R, Hinge D, Shete A, Advances in Nanocarriers for Targeted Drug Delivery: A Review .Int J Drug Deliv Technol. 2026;16(1s): 17-25; DOI: 10.25258/ijddt.16.17-25