1Undergraduate, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
2*MDS, Senior Lecturer, Department of Public Health Dentistry, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
3Postgraduate, Department of Public Health Dentistry, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
4,5MDS, Reader, Department of Public Health Dentistry, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
6PhD, Head of the Department, Department of Public Health Dentistry, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
7MDS, Professor, Department of Public Health Dentistry, SRM Dental College, Ramapuram, Bharathi Salai, Chennai.
Background: The antioxidant and anti-inflammatory qualities of blackberry anthocyanins have led to a great deal of research on their possible anticancer effects. The intricacy of anthocyanins' role in cancer is highlighted by recent research that indicates they may have pro-cancerous effects in particular situations.
Aim and Objective: This systematic review's objectives are to summarise existing research, pinpoint knowledge gaps, and guide future investigations in order to clarify the conflicting roles of blackberry anthocyanins in cancer. The aim of this systematic review is to thoroughly examine the body of research on blackberry anthocyanins and their connection to cancer, with an emphasis on figuring out the mechanisms behind their disparate effects.
Materials and Methods: Several databases, such as PubMed, Scopus, and Web of Science, were used to perform an extensive literature search. Included were studies that looked at how blackberry anthocyanins affected animal models or cancer cells. Blackberry anthocyanins, cancer, anticancer effects, and pro-cancerous effects were among the search terms.
Results: With both pro- and anti-cancerous effects documented, the review emphasises the complex role of anthocyanins in cancer. The findings imply that a number of variables, such as the anthocyanins' concentration and structure, the kind of cancer cells, and the cellular environment, may influence how blackberry anthocyanins affect cancer cells.
Conclusion: A thorough summary of the conflicting roles that blackberry anthocyanins play in cancer is given by this scientific scoping review. According to the findings, more investigation is required to elucidate the mechanisms behind these conflicting effects and investigate the potential therapeutic uses of blackberry anthocyanins in the prevention and treatment of cancer.
Keywords: NA
How to cite this article: Acharya AA, Fathima L, D D G, Rajmohan M, Dhamodhar D, Sindhu R, Prabu D. Elucidating The Contrasting Role Of Blackberry Anthocyanins In Cancer- A Scientific Scoping Review. Int J Drug Deliv Technol. 2026;16(1s): 276-288. DOI: 10.25258/ijddt.16.1s.35
Source of support: Nil.
Conflict of interest: None