1Postgraduate Student, Department of General Surgery, Chettinad Medical College and Research Institute, Chennai, Tamil Nadu, India
2Professor, Department of General Surgery, Chettinad Medical College and Research Institute, Chennai, Tamil Nadu, India
Background: Acute pancreatitis (AP) is a common gastrointestinal emergency with a clinical spectrum ranging from mild self-limiting disease to severe necrotising pancreatitis with multi-organ failure. Accurate severity stratification at admission is critical for guiding clinical management. The Modified Mortele CT Severity Index (MCTSI) was developed to address limitations of the original Balthazar CT Severity Index.
Objective: To evaluate the diagnostic and prognostic utility of the MCTSI in patients admitted with AP at a tertiary care centre.
Methods: A retrospective observational study was conducted in the Department of General Surgery, Chettinad Medical College and Research Institute, Chennai, from September 2025 to December 2025. Twenty patients aged 19–60 years with confirmed AP were included. CECT performed at 48–72 hours was used to assign MCTSI scores (mild 0–3, moderate 4–6, severe 7–10).
Results: Of 20 patients, 12 (60%) were male; mean age was 38.4 ± 11.2 years. The predominant aetiology was gallstone disease (45%). Eight patients (40%) had mild, 7 (35%) moderate, and 5 (25%) severe MCTSI scores. Mean hospital stay increased significantly across categories (5.2 vs 9.6 vs 17.8 days; p <0.001). MCTSI correlated strongly with organ failure (r=0.79), need for intervention (r=0.72), and in-hospital mortality (r=0.61; all p<0.05). One patient (5%) died, belonging to the severe category.
Conclusions: The MCTSI demonstrated a robust correlation with all measured clinical outcomes and represents a valuable evidence-based prognostic tool in AP management.
Keywords: Acute pancreatitis, Modified CT Severity Index, Mortele, MCTSI, contrast-enhanced CT, severity scoring, prognosis.
How to cite this article: Kumar DL, PA J, Kumar P, Prabakar A. Mortele Modified Ct Severity Index In Acute Pancreatitis: A Retrospective Observational Study From A Tertiary Care Centre. Int J Drug Deliv Technol. 2026;16(1s): 289-302. DOI: 10.25258/ijddt.16.1s.36
Source of support: Nil.
Conflict of interest: None