Optimizing Graft Versus Host Disease Mitigation Strategies In Allogeneic Stem Cell Transplantation For Myelodysplastic Syndromes Progressing To Acute Myeloid Leukemia: A Systematic Evaluation Of Evidence Based Immune Modulatory Approaches

Dr Birupaksha Biswas ¹, Dr. Jayashree Konar ², Dr. Suhena Sarkar³, Mr.Masud Rana⁴, Mr Shovan Konar⁵, Mr.Akash Ghosh⁶

¹MBBS, MD(Clinical & Interventional Pathology), Senior Resident, Department of Pathology,West Bengal University of Health Sciences , Email ID : drbiswasmd@aol.com ,ORCID iD- 0009-0007-5701-9131,
²MBBS(Hons.), MD( MICROBIOLOGY), DNB(MICROBIOLOGY) ,Associate Professor (Department of Microbiology),College of Medicine & Sagore Dutta Hospital ,Kolkata- 700058, Email ID :  jayashreek742@gmail.com , ,ORCID id: 0000-0001-9141-8768
³MBBS(Hons), MD ,Associate Professor Department of Pharmacology, Medical College, Kolkata, India Email ID :,suhena.m@gmail.com, ORCID iD- 0000-0002-7430-4643
⁴Degrees - BMLT,PG -MLT Affiliation- Assistant professor in Islamia Hospital. Email ID : masudtownclub555@gmail.com
⁵Degree- PG-MLT (MLT Microbiology,Sevayatan School of Medical Technology , Singur ) Affiliation - Regional VRDL , AIIMS PATNA ,Phulwarisharif , Patna , Bihar , India- 801507 . Email ID : iamshovankonar@gmail.com, ORCID iD :0009-0004-7905-987X
⁶Department- Bachelor of Medical Laboratory Technologist Hons.(BMLT HONS.),Chandigarh University, ORCID iD:0009-0001-2236-3000, Email ID : clinicaltechresearcherghosh08@gmail.com.

ABSTRACT

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Keywords: Allogeneic transplantation, graft immunobiology, post transplant cyclophosphamide, ex vivo T cell depletion, graft versus host modulation, hematopoietic immune reconstitution, non relapse mortality dynamics, cytokine mediated allo inflammation, donor recipient immune equilibrium, transplant immunoprophylaxis optimization.

How to cite this article: Biswas B, Konar J, Sarkar S, Rana M, Konar S, Ghosh A. Optimizing Graft Versus Host Disease Mitigation Strategies In Allogeneic Stem Cell Transplantation For Myelodysplastic Syndromes Progressing To Acute Myeloid Leukemia: A Systematic Evaluation Of Evidence Based Immune Modulatory Approaches..Int J Drug Deliv Technol. 2026;16(1s): 357-370; DOI: 10.25258/ijddt.16. 357-370