International Journal of Drug Delivery Technology
Volume 16, Issue 1s

A rare case report: ALCAPA (Bland - White-Garland syndrome) - Congenital heart disease

Dr S Bharath simha reddy 1, Dr Vineeta Pande 2, Meda Maansi 3

1MBBS, MD Resident in paediatrics, Department of Peadiatrics, Dr. D. Y. Patil Vidyapeeth (Deemed to be university) ,pimpri ,pune -411018, India
2MD Paediatics,DCH , Professor Department of Paeciamics Dr D. Y. Patil Medical College, Hospital & Research Centre , Dr D.Y Patil Vidyapeth (Deemed to be university) pimpri Pune-411018, India Email-ld drvineetapande@gmail.com
3Dr D. Y. Patil Medical College, Hospital & Research Centre , Dr D.Y Patil Vidyapeth (Deemed to be university) pimpri Pune-411018, India Email ID : maansimeda15@gmail.com


ABSTRACT

Background:Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA), also known as Bland-White-Garland syndrome, is a rare but potentially fatal congenital heart defect. It constitutes approximately 0.25% to 0.5% of all congenital cardiac malformations, with a reported incidence of nearly 1 per 300,000 live births, particularly noted in the infant population (1 year) in India. Case Summary: A 4 -month-old male child was presented with complaints of sudden onset increased work of breathing for the past one day, which worsened during feeding and was associated with increased irritability and sweating during feeds. There was no history of fever, cold, cough, or weight loss .Respiratory system examination was towards normal then referral to a pediatric cardiologist and subsequent echocardiography revealed a dilated dysfunctional left ventricle, severe mitral regurgitation (MR), moderate tricuspid regurgitation (TR), and a suspicion of Anomalous Left Coronary Artery from the Pulmonary Artery (ALCAPA) was confirmed by cardiac CT . The child was subsequently admitted and managed conservatively. Surgical intervention was later advised as part of the treatment plan. Conclusion:The case underlines the importance of high clinical suspicion, early referral, and multidisciplinary care in managing congenital heart diseases like ALCAPA, where surgical correction remains the definitive treatment to prevent long-term cardiac complications and mortality.

Keywords: ALCAPA, Congenital Heart Diseases, Outcome

How to cite this article: Reddy SBS, Pande V, Maansi M., A rare case report: ALCAPA (Bland - White-Garland syndrome) - Congenital heart disease.Int J Drug Deliv Technol. 2026;16(1s): 429-431; DOI: 10.25258/ijddt.16. 429-431