Nanoemulsions as Drug Delivery Systems: Stability and Applications

Leena Deshpande ¹, Ajab Singh Choudhary ², Mehul Kumar Choudhary ³, Mr. Shivsharan Dhadde ⁴, Mr. Anup Patil ⁵, Dr. Dilip Hinge⁶

¹Associate Professor Department of Computer Engineering – Software Engineering Vishwakarma Institute of Technology Pune, Maharashtra – 411037, India Email: leena.deshpande@vit.edu
²Assistant Professor School of Allied Health Sciences Noida International University Uttar Pradesh – 203201, India Email: ajab.singh@niu.edu.in
³Assistant Professor Department of Pharmaceutics Arya College of Pharmacy Jaipur, Rajasthan, India Email: mehul.kumar@aryajaipur.com
⁴Assistant Professor Department of Pharmacology Krishna Institute of Pharmacy Krishna Vishwa Vidyapeeth (Deemed to be University) Taluka-Karad, Dist-Satara – 415539 Maharashtra, India Email: sbdhadde@hotmail.com
⁵Associate Professor Department of Pharmacology Krishna Institute of Pharmacy Krishna Vishwa Vidyapeeth (Deemed to be University) Taluka-Karad, Dist-Satara – 415539 Maharashtra, India Email: anuppatil.pharma@gmail.com
⁶Assistant Professor Krishna Institute of Science and Technology Krishna Vishwa Vidyapeeth (Deemed to be University) Taluka-Karad, Dist-Satara – 415539 Maharashtra, India Email: ddhinge@gmail.com

ABSTRACT

Because they can function like biological processes and increase the efficacy of treatments, bioinspired nanocarriers seem Nanoemulsions are getting more and more attention as improved drug delivery methods because they can make drugs that don't dissolve well in water more stable and bioavailable. These very small emulsions, usually between 20 and 200 nm, have an oil phase, a water phase, and agents that help both lipophilic and hydrophilic chemicals get trapped inside them. Nanoemulsions' safety depends on many things, such as the type and amount of detergents used, the way they are made, and the qualities of the drug they are encasing. However, outside factors like temperature, pH, and ionic strength can make them less stable, which can cause phases to separate, coalescence, or aggregation. To make sure that nanoemulsion-based drug delivery methods work well, it is important to make sure that the mixture is stable. Nanoemulsions are used in many therapeutic areas to give drugs, such as cancer treatment, drug delivery through the mouth or skin, and specific drug delivery. Nanoemulsions have a lot of potential for cancer treatment because they can make anticancer drugs more soluble and control how much they get into healthy cells, so they are less harmful to them. Nanoemulsions help badly soluble drugs be absorbed when they are taken by mouth, which improves solubility and treatment results. Adding targeted molecules to nanoemulsion formulations also makes it possible for drug transport to specific sites, which improves efficiency and lowers side effects. Nanoemulsion-based drug delivery systems have many benefits, but they need to be commercialised. To do this, problems like large-scale production, long-term safety, and legal issues need to be solved. More study into how to make and improve nanoemulsions could completely change how drugs are delivered and lead to new ways to make treatments work better and improve patient results.

Keywords: Nanoemulsions, Drug Delivery Systems, Stability, Bioavailability, Cancer Therapy.

How to cite this article: Deshpande L, Choudhary AS, Choudhary MK, Dhadde S, Patil A, Hinge D, Nanoemulsions as Drug Delivery Systems: Stability and Applications.Int J Drug Deliv Technol. 2026;16(1s): 58-66; DOI: 10.25258/ijddt.16. 58-66