Postpartum depression (PPD) is a prevalent psychiatric disorder in postpartum women, characterized by persistent dysphoria, diminished hedonic responsiveness, persistent depressive affect, and self-devaluation, accompanied by significant emotional and cognitive impairment. PPD shares features with major depression but is influenced by unique physiological and psychological changes associated with childbirth. Long-term impacts of PPD can affect maternal functioning, mother-infant bonding, and child development. Understanding the scope and impact of PPD has significant implications for both healthcare providers and researchers. Early detection, the promotion of effective breastfeeding practices, and the provision of holistic postpartum care are crucial in reducing the potential risks linked to postpartum depression (PPD). Furthermore, the complex hormonal and physiological changes that occur during and after pregnancy may affect women mental health. In order to improve the quality and consistency of future research, prioritizing the early identification of PPD and adopting integrated, comprehensive postpartum care approaches are essential for effectively addressing the challenges associated with this condition. Further research is imperative to elucidate the potential protective effects of breastfeeding and to inform the development of evidence-based interventions designed to enhance maternal mental health and optimize infant developmental outcomes..
Keywords: Postpartum depression, pathophysiology, pharmacology, therapeutics, recovery.
How to cite this article:Gonsalves L, Singh P; Postpartum Depression and its Neuropsychological Sequelae in Children: An Evidence- Based Synthesis..Int J Drug Deliv Technol. 2026;16(1s): 635-649; DOI: 10.25258/ijddt.16. 635-649